Your Guide to Drug-Induced Nutrient Depletion

Your Guide to Drug-Induced Nutrient Depletion
Photo by JOSHUA COLEMAN on Unsplash

By Kristen M. Leccese

All too often, our health issues require prescription or over-the-counter medications in order to resolve themselves. Certain drugs – including opiate painkillers, blood pressure medications, corticosteroids, antibiotics, tricyclic antidepressants, and even OTC drugs as innocent as aspirin and antacids – are all capable of causing severe nutrient depletions in our bodies.  This absence of important nutrients like Folic Acid, Beta-Carotene, Potassium, and endless other naturally-occurring chemicals in our bodies can lead to unpleasant side effects and an overall imbalance in your system.

Whether you occasionally take a pharmaceutical like an antibiotic, or count on a drug long term such as a cholesterol health lowering statin, your need for specific nutrients increases. You must be aware that many prescriptions, as well as commonly used over-the-counter drugs, cause potentially serious nutrient depletions. For your convenience, we here at InVite® Health have devised a Drug-Induced Nutrient Depletion Chart with a list of drugs and non-prescription medications and the nutrients they deplete. This in turn will give you an idea of the nutrients your body needs, which can be found in our high-quality InVite® Health supplements.

Below, our handy Drug-Induced Nutrient Depletion chart lets you know exactly what nutrients your prescription or OTC medications are depleting:






Narcotic for pain relief Folic Acid, Vitamin C, Iron, Potassium

Statin Drugs

Lipitor, Crestor, Lescol,
Pravachol, Zocor, Mevacor

Lowering Cholesterol Coenzyme Q10

ACE Inhibitor

Lisinopril. Altace, Accupril,
Capoten, Prinivil, Zestril, Vasotec

High Blood Pressure Zinc

Thiazide Diuretic


High Blood Pressure Vitamin D, Calcium, Magnesium,
Phosphorus, Potassium, Zinc, Coenzyme Q10

Beta Blocking Drugs

Atenolol, Corgard, Lopressor, Tenormin, Toprol XL, Metoprolol

High Blood Pressure Coenzyme Q10, Chromium, Melatonin

Loop Diuretic

Furosemide,, Lasix, Ethacrynic acid,
Edecrin, Bumex,

High Blood Pressure, Heart Failure B1, B6, Vitamin C, Calcium, Magnesium,
Phosphorus, Potassium, Zinc

Proton Pump inhibitor

Omeprazole, Prilosec, Prevacid,
Nexium, Protonix, Aciphex

GERD, severe gastric ulceration Beta-carotene, B1,
B12, Folic Acid, Calcium, Zinc


Metformin, Glucophage

Diabetes, Pre-diabetes Folic Acid, B12


Fosamax, Actonel, Boniva,
Didronel, Skelid

Osteoporosis Calcium, Magnesium, Phosphorus


Flonase, Beclovent, Beconase, QVar,
Vancenase, Vanceril

Asthma, Allergic Rhinitis Beta-Carotene, B6, Folic Acid,
Vitamin C, Vitamin D, Calcium, Magnesium,
Potassium, Selenium, Zinc, Melatonin

Fluoroquinolone Antibiotic

Levaquin, Avelox, Cipro, Floxin, Noroxin,
Penetrex, Trovan

Bacterial Infection Biotin, B1, B2, B3, B6, B12, Zinc,
Healthy intestinal bacteria

Conjugated Estrogen

Premarin Hormone replacement therapy,
birth control pills

Hormone Replacement Therapy B6, Vitamin D, Calcium, Magnesium, Zinc,
Folic Acid, B12

Beta-2 Adrenergic Receptor Agonist

albuterol aerosol
Brethine, Proventil, Tornalate, Ventolin,

Asthma, COPD Potassium, and possibly Calcium,
Magnesium, Phosphorus


Prednisone, Deltasone, Celestone,
Cortisone, Cortef, Cortone,
Dexamethasone, Decadron, Hydrocortone,
Medrol, Methylprednisolone

Severe Inflammation, Autoimmune
Disease, Immune System Suppression
Beta-Carotene, B6, Folic Acid,
Vitamin C, Vitamin D, Calcium, Magnesium,
Potassium, Selenium, Zinc

Calcium Channel Blocking Drugs

• amlodipine (Norvasc)
• felodipine (Plendil)
• nifedipine (Procardia, Adalat)
• nimodipine (Nimotop)
• nisoldipine (Sular)

High Blood Pressure Vitamin D


glyburide, glipizide, glimepiride,
Amaryl, Diabeta, Glucotrol,
Glynase, Micronase

Diabetes Coenzyme Q10

Cardiac Glycoside

Digoxin, Digitek, Lanoxin,

Heart Failure, Arrhythmias Calcium Magnesium,
Phosphorus, Potassium, B1

Penicillin Antibiotic

Amoxicillin, Amoxil, Trimox, Penicillin

Infection Healthy Intestinal Bacteria, B1, B2, B3, B6,
B12, Vitamin k, Folic Acid, Biotin, Inositol

Macrolide Antibiotics

Erythromycin, Azithromycin,
Biaxin, Zithromax

Infection Healthy Intestinal Bacteria,
B1, B2, B3, B6, B12,
Vitamin k, Folic Acid, Biotin, Inositol

Tricyclic Antidepressants

amitriptyline, clomipramine,
doxepin imipramine,
Anafranil, Asendin, Elavil,
Tofranil, Vivactil

Depression Coenzyme Q10, B2,

Potassium Sparing Diuretics

amiloride, spironolactone, triamterene,
Aldactone, Dyazide, Dyrenium, Maxzide

Heart Failure, High Blood Pressure Calcium, Magnesium, Phosphorus
Watch for a high Potassium level

OTC (non-prescription medication)


Ibuprofen, naproxen and other
Arthritis drugs

Inflammation, Pain Folic Acid


Pain, Inflammation, Fever (adults) Folic Acid, Vitamin C,
Iron, Potassium, Zinc



Pain, Fever Coenzyme Q10, Glutathione


Amphojel, Basaljel,
Aluminum Hydroxide plus Magnesium,
Gaviscon, Gelusil, Maalox, Mylanta

Gastritis, GERD Beta-Carotene, Folic Acid, Vitamin D,
Calcium,Chromium, Iron, Zinc,
Magnesium, Phosphorus

Laxatives with Bisacodyl

Carter’s Little Pills, Correctol, Dulcolax,
Feen-a-Mint, PMS-Bisacodyl

Constipation Calcium, Potassium

H2 Inhibitors

Famotidine, Pepcid,
Tagamet, Zantac

Ulcer, GERD Folic Acid, B1, B12, Vitamin D,
Iron, Zinc

Please note: Beta-Carotene represents Vitamin A depletion.
Related drugs are listed because in many cases there is a similar depletion profile.

* The statements herein have not been evaluated by the Food and Drug Administration.
These products are not intended to treat, diagnose, cure, or prevent any diseases.

Our on-site Naturopathic Doctors at any InVite Health’s twelve retail locations can help out with any questions or concerns you may have about this information, as well as assist in choosing the correct supplement for you. Stop in for a free nutritional consultation, or email us at [email protected]. You can also click here to fill out our free nutritional consultation form online!


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