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Diabetes Lab Tests

Diabetes Lab Tests

Diabetes Lab tests Written by: Dr. Claire Arcidiacono, ND For further questions or concerns email me at carcidiacono@invitehealth.com† Diabetes is ruled out or confirmed with blood tests. One of the most important tests is A1c or hemoglobin A1c (hA1C). This measures the average blood sugar levels 

Ladies, hormones getting you down? Help is here!

Ladies, hormones getting you down? Help is here!

regulating hormones Please see below for a complete transcript of this episode. Hosted by Amanda Williams MD, MPH *Intro Music* InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InVite Health podcast, where our degreed health care professionals are excited to offer you the most important 

Targeted Nutrients to Support Breast Health

Targeted Nutrients to Support Breast Health

breast

Targeted Nutrients to Support Breast Health
By: Kayanne McDermott, ND

For further questions or concerns email me at kmcdermott@invitehealth.com†

According to the World Cancer Research Fund International, Breast Cancer came up in top rank as one of the top 3 cancers in women worldwide in 2020 (1). In addition, breast cancer ranks second as cause for cancer related death in women (2). There are many possible contributing factors to the development of breast cancer, some could be due to genetics, environmental influence, iatrogenic, lifestyle influences & there’s a small percent of unknown cause. You may not have had breast cancer, or perhaps you’re a survivor or may know someone who may have had it, or  currently fighting it now. You may have lost a mom, sister, aunt or loved one to breast cancer and you want to know if you can prevent it or lessen your chances of being diagnosed of having breast cancer. In this article, I’m going to discuss a little bit about breast cancer, the correlation with estrogen dominance, and what can be done nutritionally to support your immune system to withstand this terrible diagnosis and what can be done to lessen the risk of developing breast cancer.†

Breast Cancer is a type of cancer that starts in the breast, and cancer in general is abnormal cells that grows rapidly out of control(3). Breast cancer can be benign or malignant, there are subtypes and they can also be located in different regions of the breast, such as in the lobules, ducts, stroma and/or nipples, and depending on the location, they will be named as such, for example, if cancer is found in the ducts of the breast, it would be ductal cancer or in the lobes, lobular cancer. It’s not exactly that simple, but the name will give you an idea of the location of the cancer in the breast. Breast cancer can spread to the rest of the body when it gets into the lymph nodes or into the blood.†

Estrogen Dominance is when there’s an imbalance of the hormones, estrogen and progesterone. Progesterone can be too low, causing estrogen dominance or there can be an excess of estrogen due to gut flora imbalance, poor liver health, environmental toxicity due to xenoestrogens, and/or chronic stress. Not all breast cancers are created equal, therefore finding out which type of hormones influence the growth of breast cancer, determines the therapy. This can be done by getting a hormone receptor test. Therefore before taking any nutritional supplements, finding out the breast cancer type is imperative. However if you’re taking a preventative approach, then there’s no need for that test. There’s also a genetic test that can be done to check your susceptibility of developing breast cancer, given there’s a family history of breast cancer.†

THE GUT-ESTROGEN CONNECTION>>Read Now!

How can one manage breast cancer alternatively? Well, I wouldn’t recommend to rule out the conventional way of doing things completely, therefore I would suggest that you work with the oncologist that understands your view and preferences on treatment so that they can support you the best way they can with integrating both the conventional and non-conventional approach. In addition to having a diet rich in leafy green & cruciferous vegetables, organic berries, healthy fats and high fiber, employing some additional supplements may be helpful in supporting your efforts in combatting or preventing this dreadful diagnosis. When it comes to overcoming any forms of dis-ease, it takes mental, emotional & physical effort. I won’t get into emotional or mental today, however I will focus on what can be done nutritionally to support you.†

Indole-3-carbinol with Diindolylmethane (I3Cw/DIM) has shown to break down the estrogens your body doesn’t need so that they can be eliminated through your stool and/or urine. Studies have shown that these compounds has anti-estrogenic activity, and protects against tumor formation, (5). This is a naturally occurring compound that is found in cruciferous & brassica vegetables such as broccoli, cabbage, & brussel sprouts. Invite’s I3Cw/DIM provides support against the bad estrogens, enhancing estrogen metabolism and may prevent the development of estrogen-enhanced cancers such as breast cancer, (6).†

Green Tea, another potent “miracle” in a cup or in this case, bottle. Green tea contains many phytonutrients, antioxidants, catechins & polyphenols. Due to its (7)catechin content, studies have shown that Green tea has anti-cancer, anti-viral and antioxidants effects, inhibiting cancer cell proliferation (8). Epigallocatechin-3- gallate (EGCG), a powerful polyphenolic compound in green tea, has been studied to show apoptotic, anti-metastatic & anti-angiogenic effects when taken orally, (9). With such a study, one will want to get on the band wagon of drinking green tea daily, due to the outstanding benefits it holds.†

There’s so much that can be discussed about breast health and nutrition, however I’m going to just highlight one more nutrient that can be easily overlooked to be helpful for breast health. That nutrient is, Vitamin D! It’s mostly highlighted for bone, and immune health, however, Vitamin D can be very beneficial in supporting breast tissue. Every organ in our body has a Vitamin D receptor including the breast tissue. Vitamin D is obtained from the sun via UV rays through our skin then synthesized primarily, by the kidneys into it’s active form, 1-25 dihydroxy-Vitamin D3. Studies have shown that there’s a correlation between Vitamin D deficiency and increased risk of breast cancer, (10). According to The Journal of Steroid Biochemistry and Molecular Biology, when there’s a reduction of Vitamin D Receptor expression within breast cancer cells, this can accelerate tumor progression and enable metastases, (11). With having information like this, I highly recommend that you implement Vitamin D supplement into your daily regimen, including men. Men, may not have breast cancer, which men can attain as well, but that’s in the low percentile. You may not  have abnormal breast tissue, nor any kind of abnormality, however taking Vitamin D3, should be that one vitamin that you do not go without as part of your daily regimen. There’s a saying that goes, “Prevention is better than cure.” Have your Vitamin D blood levels checked, so that you will know the amount you need to maintain optimal levels.†

NEW FINDINGS ON NUTRITION AND CANCER – INVITE HEALTH PODCAST, EPISODE 501>>Listen Now!

If you or someone that you know that may be experiencing or have had breast cancer or abnormal mammogram results, I suggest that you or they, implement the above supplements to enhance their prognosis. In addition, what you eat and consume on a daily basis goes a long way. Implement a lot of cruciferous vegetables, healthy fats, whole grains, tons of berries and exercise into your daily regimen. If you have a family history of breast cancer or any other reproductive abnormality, speak to your endocrinologist, Ob/Gyn, get the correct tests done and work with an Invite Health degreed professional to help you get on track.†

If you have any questions, concerns, you can email me at kmcdermott@invitehealth.com.

 

Resources:
1. https://www.wcrf.org/cancer-trends/worldwide-cancer-data
2. Mohammad Fahad Ullah. (2019). “Breast Cancer: Current Perspecitives on the Disease Status”. Advanced in experimental medicine and Biology. PMID: 31456179
3. Cancer.org. “What is Breast Cancer?”
4. Lynch, Ben ND. (2018). “Dirty Genes: A breakthrough Program to treat the root cause of illness and optimize your health.” 1st Edition. HarperOne, New York, NY.
5. Cover,Carolyn; S. Jean Hseih; Cram, J Erin; Hong, Chibo; Riby, Jacques E; Bjeldane,Leonard F; Firestone,Gary L. (1999). “Indole 3 Carbinol and Tamoxifen Cooperate to Arrest the Cell Cycle of MCF-7 Human Breast Cancer Cells”. American Association of Cancer Research; Experimental Therapeutics; Volume 59: Issue 6.
6. Karen J Auborn , Saijun Fan, Eliot M Rosen, Leslie Goodwin, Alamelu Chandraskaren, David E Williams, DaZhi Chen, Timothy H Carter. (2003). “Indole-3-carbinol is a negative regulator of estrogen.” Journal of Nutrition.
7. Tiantian Zhao, Chao Li,2 Shuai Wang, and Xinqiang Song. (June 2022). ” Green Tea (Camellia Sinensis): A Review of its Phytochemistry, Pharmacology, and Toxicology.” Molecules. Volume 27; Issue 12. PMCID: PMC9231383
8. Tommaso Filippini, Marcella Malavolti, Francesca Borrelli, Angelo A Izzo, Susan J Fairweather-Tait, Markus Horneber, Marco Vinceti. (2020, March 2). ” Green Tea (Camellia Sinensis) for the prevention of cancer.” The Cochrane Database of Systematic Reviews. PMCID: PMC7059963
9. Adriana Romano, Fátima Martel. (2021). “The Role of EGCG in Breast Cancer Prevention and Therapy.” Mini Reviews in Medicinal Chemistry. PMID: 33319659
10. Kay W.Colston PhD. (August 2008). “Vitamin D and breast cancer risk.” Best Practice & Research Clinical Endocrinology & Metabolism. Volume 22, Issue 4, Pages 587-599. https://doi.org/10.1016/j.beem.2008.08.002
11. Abhishek Aggarwal, David Feldman, Brian J Feldman. (March 2018). “Identification of tumor-autonomous and indirect effects of vitamin D action that inhibit breast cancer growth and tumor progression.” The Journal of Steroid Biochemistry & Molecular Biology. Volume 177, Pages 155-158. PMID: 28710021 PMCID: PMC5764828 DOI: 10.1016/j.jsbmb.2017.07.003.

Summary of Digestive Health

Summary of Digestive Health

Dr.Claire concludes her series by summarizing the most common digestive health issues that occur among many individuals.

The Gut-Estrogen Connection

The Gut-Estrogen Connection

Dr.Kay speaks about the impact of the gut microbiome connection with the hormone estrogen and the importance of maintaining their balance.

Digestive Health Part 13: SIBO

Digestive Health Part 13: SIBO

Written by Dr. Claire Arcidiacono, ND SIBO

For further questions or concerns email me at carcidiacono@invitehealth.com†

Our very last topic is small intestinal bacterial overgrowth or SIBO for short. SIBO is an imbalance of bacteria in the small intestine where one type of bacteria in the intestines takes over. Normally, the bacteria in the small intestine is balanced, with no one type being dominant. This balance is maintained by the presence of many types of  “good” bacteria, gastric or stomach acid, bile, enzymes, and immunoglobulins.  For different reasons, these control mechanisms can fail and the bacteria balance tips in favor of 1 type of bacteria who then proceed to overgrow. (1)

ICYMI: DIGESTIVE HEALTH PART 12: MORE ACID >> Read Now!

What are the signs of SIBO? Normally there is diarrhea and occasionally constipation. However, in my clinical experience, constipation happens more than you would expect. There is often gas, bloating, nausea with occasional vomiting, uncomfortable feeling of fullness or even outright abdominal pain. Loss of appetite often leads to weight loss as well as malnutrition. Systemic symptoms of SIBO include brain fog, fatigue, joint pain, insomnia, and is even associated with low B12. (2)

SIBO is normally determined by a breath test. The bacteria breakdown lactulose; when you breathe out you expel the hydrogen (H2), methane (H4) or Hydrogen sulfide (H2s) produced by the bacteria. The H2 predominant form of SlBO is associated more closely with diarrhea while the H4 predominant form of SIBO is more closely related to constipation. (3)

What are the risk factors for SIBO?  Anything that prevents food from moving through the small intestines properly. As the food stays in the small intestine, the bacteria grow faster than expected. Things that can cause the food to move too slowly through the small intestine include low stomach/gastric acid, any physical changes in the intestines including those that are congenital, as well as stress and anxiety. Other risk factors include surgical procedures such as gastric bypass, and surgery/radiation treatments. Any injury to the small intestine including anal fistulas and blockages in the GI tract are also risk factors for SIBO. IBD both Crohn’s and Ulcerative colitis are also risk factors. There are also systemic medical concerns that can increase the risk of SIBO. These include HIV, immunoglobulin A deficiency as well as diabetes and lupus. Medications such as antibiotics, PPIs, certain medications for IBS as well as narcotics all increase the risk of SIBO. (4)

DIGESTIVE HEALTH PART 11: TOO MUCH ACID >> Read Now!

Treatment for SIBO is much more complex than just taking a probiotic to help restore balance to the digestive tract. The reason is that SIBO is an overgrowth of bacteria. In my clinical experience, it appears to usually be bad or pathogenic bacteria. However, in some individuals, it appears that the overgrowth is caused by what is normally considered “good” bacteria. Therefore it is hypothetically possible a bacteria based probiotic could make the situation worse. Therefore, changing the “terrain” to reduce the risk of bacteria overgrowth is important in working with SIBO. Interestingly, yeast based probiotics do not have this concern. (5) Since SIBO is an overgrowth of bacteria, antibiotics are used to kill the bacteria. The next conventional recommendation is to follow a low fodmap diet. Eliminating any foods that increase symptoms is also important. Lastly if there are any underlying concerns such as diabetes, lupus, crohn’s or diverticulosis for example those need to be addressed first. (2).

In order to work with SIBO there is a more systematic approach that is helpful:

  • We must regulate the overgrowth of bacteria
  • We must increase the immune system as well as normalize the transit of food through the small intestine to avoid bacterial overgrowth
  • We must heal the damage caused by SIBO
  • Once a negative test is achieved and we know that the terrain is healthy, we must repopulate the small intestine with a good quality probiotic. (3)

 

Supplement Suggestions: SIBO

  • Garlic has been found in studies to help eliminate bacteria as well as fungus such as Candida. (6) See Invite’s Nutristatin 144 as well as our Aged Garlic!
  • Olive leaf extract has also been found to help eliminate microbes such as yeast in the body. (7). See Invite’s Olive leaf extract as well as our Renalaid formula!
  • Studies show that Saccharomyces can help with the symptoms of SIBO. (8) See Sacro-B a fabulous product offered by Invite!
  • Colostrum is amazing when it comes to fighting off pathogens in the digestive tract. Colostrum helps to kill pathogens directly, boost the immune system and builds up the mucus layer which is part of what protects the digestive system from being damaged. (9) Please see Invite’s Colostrum, and our powered colostrum called Neuroimmune!
  • Nucleotides, while not usually a supplement associated with the gut, has been found in studies to be helpful in working with boosting the immune system as well as promoting healing (10) Please see Invites Nucleotide complex!
  • Demulcent herbs have been found to be helpful in lowering inflammation and any damage done in the digestive tract as well as reducing the incidence of opportunistic infection. This is important in working with SIBO because the bacteria often cause irritation in the digestive tract and can even lead to leaky gut. These demulcent herbs can include the following: DGL, Aloe Vera, Slippery Elm and Marshmallow root. (11) Please see Invite’s G.I Maintain Maintain, Min Acid and DGL.
  • In the case of low stomach acid, there has been found to be a correlating low level of zinc as well as B vitamins. Correcting these deficiencies will eliminate the underlying cause of the slow transit time through the small intestine, one of the causes of SIBO (12) . Please see Invite’s Zinc products as well as our line of B vitamins!
  • Digestive enzymes can help to break down the food and help to replace the acid missing due to low stomach acid. Once again, this helps with the low transit time that is a risk factor for SIBO (13) Please see Invite’s Digestive Hx and Prozyme digest.
  • It is important to address any diarrhea or constipation as well as stress.

We have officially completed the digestive series! There will be a summary and then we’ll moving on to our next topic.

Sources

  1. Johns Hopkins Medicine: “Small Intestinal Bacterial Overgrowth (SIBO).”
  2. https://www.webmd.com/digestive-disorders/sibo-overview-what-is-it#091e9c5e81c61a6a-1-1
  3. https://oc-integrative-medicine.com/do-you-have-sibo/
  4. Cleveland Clinic: “Small Bowel Bacterial Overgrowth.”
  5. https://health.usnews.com/health-news/blogs/eat-run/articles/2018-06-21/4-facts-about-sibo-the-internet-keeps-getting-wrong
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458355/
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490280/#:~:text=The%20present%20stud
  8. https://www.optibacprobiotics.com/professionals/latest-research/gut-health/sibo-probiotics
  9. https://www.nature.com/articles/s41598-019-39644-x
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146642/
  11. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065514/
  12. https://www.clinicaleducation.org/resources/reviews/the-role-of-hcl-in-gastric-function-and-health/
  13. https://www.hopkinsmedicine.org/health/wellness-and-prevention/digestive-enzymes-and-digestive-enzyme-supplements