Tag: memory

Alzheimer’s Disease, Part 3, Invite Health Blog

Alzheimer’s Disease, Part 3, Invite Health Blog

Written by: Dr. Claire Arcidiacono, ND For further questions or concerns email me at carcidiacono@invitehealth.com†   Alzheimer’s is a complex disease with many risk factors. It is a disease that affects more than just the person who is afflicted with the illness. For the care takers 

Collagen & The Brain, Invite Health Podcast, Episode 658

Collagen & The Brain, Invite Health Podcast, Episode 658

Subscribe Today! Please see below for a complete transcript of this episode. COLLAGEN & THE BRAIN, INVITEⓇ HEALTH PODCAST, EPISODE 658 Hosted by Jerry Hickey, Ph. *Intro Music* InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed health care professionals 

ALZHEIMER’S DISEASE, Part 2, Invite Health Blog

ALZHEIMER’S DISEASE, Part 2, Invite Health Blog

Written by: Dr. Claire Arcidiacono, ND

For further questions or concerns email me at carcidiacono@invitehealth.com†

 

In our last blog we started talking about Alzheimer disease. We began our discussion with talking about what it is, how it affects the brain and also what are the signs and symptoms you should look out for? Today we will cover the risk factors for developing the disease as well as how it is diagnosed. In our very last blog, we will review methods to help with symptoms management/reduce the risk factors. †

One of the most important risk factors for developing Alzheimer’s disease (AD) is age. After age 65 the risk of developing AD increases each year. Unfortunately, it doubles every 5 years after you reach 65. This means that by the time you reach age 85 the risk of developing AD is as high as 1 in 3! (1) Another risk factor is having a family history of the disease. The more family members that have the disease the greater the risk of developing it. Without getting too complicated, there are basically 2 “types” of genes. Those that determine if you get a disease without outside influence and those that increase the risks of a disease but are influenced by environmental factors. AD has been found to be associated with genes in both categories. (2) Race has also been found to increase the risk of developing AD. While it is not exactly understood why studies show that older Latinos are 1 1/2X more likely to develop AD than whites. African Americans are about twice as likely to develop the disease. (1) Now while these risk factors may be unchangeable it is still important to recognize them. †

ICYMI: ALZHEIMER’S DISEASE, PART 1, INVITE HEALTH BLOG>>READ NOW!

RISK FACTORS 

While some risk factors such as age are unchangeable, others can be influenced. For example, receiving head injuries when younger does increase the risk of developing AD as you age.  (3) Newer studies have linked heart health to AD. The risk of AD increases in those with any disease that affects the blood vessels. These include but are not limited to heart disease, diabetes, stroke, high blood pressure and high cholesterol. † (4)

AD is also believed to occur when certain proteins such as Tau proteins build up in the brain. AD is also believed to occur when abnormal amyloid beta peptides begin to accumulate and build up into amyloid plaques. This plaque leads to changes in the normal function of the brain. While it is not completely understood why this build up occurs it is believed that it may be related to age as well as brain cholesterol. (5) The presence of these plaques is a big risk factor, and it is being considered as one of the causes of AD.†

Another risk factor is the presence of oxidative stress which leads to chronic inflammation. Spirochete infections have been linked to this inflammation. (6) Sleep changes have also been linked to the inflammation in AD. While previously sleeping changes were seen as a symptom of AD in more recent time studies have suggested they are actually a risk factor for the disease. † (7)

Another possible risk factor is the balance/ homeostasis of the minerals copper, zinc and iron in the body. (8) Smoking is a huge risk factor for developing AD. (9) Along a similar pathway exposure to air pollution is also a huge risk factor. (8)  A 2018 study found an association between celiac disease and AD. (10) Obesity as well as any disease that promotes chronic inflammation may also increase the risk of AD. † (11)

At this time AD can only be diagnosed completely with an autopsy. Clinical diagnoses are therefore classified as “possible” or probable. This diagnosis is based on medical history, history from relatives as well as behavioral observations. Additionally, there are neurological and neuropsychological changes that are not explained by other conditions. (12) If you recall the blog on brain tests, you will recall that the tests can include CT scans, SPECT and PET scan which can all be used to help rule out forms of dementia including AD. Lastly as you might recall the neuropsychological tests used include the mini mental state examination. The Montreal cognitive assessment and the mini cog exam. While testing for AD may include other rule out tests, I will refer you to my blogs on brain tests. As I’ve said before it is important to always follow up with your doctor if you feel something isn’t right with your body. †

In our next blog we will be reviewing supplements that can help with known risk factors as well as review some supplements that studies show can be help with AD and dementia. These will include some you may not expect such as Turmeric! †

ALZHEIMER’S DISEASE, IMPORTANT NEW STRATEGY. INVITE HEALTH PODCAST, EPISODE 595>>LISTEN NOW!

 

REFERENCES

  1. https://www.alz.org/alzheimers-dementia/what-is-alzheimers/causes-and-risk-factors
  2. https://www.alz.org/alzheimers-dementia/what-is-alzheimers/causes-and-risk-factors/genetics
  3. https://www.alz.org/alzheimers-dementia/what-is-dementia/related_conditions/traumatic-brain-injury
  4. https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of-dementia/vascular-dementia
  5. Wang H, Kulas JA, Wang C, Holtzman DM, Ferris HA, Hansen SB (August 2021). “Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol”. Proceedings of the National Academy of Sciences of the United States of America. 118 (33): e2102191118. Bibcode:.11802191W. doi:10.1073/pnas.2102191118. PMC 8379952. PMID 34385305.
  6. Sinyor B, Mineo J, Ochner C (June 2020). “Alzheimer’s Disease, Inflammation, and the Role of Antioxidants”. Journal of Alzheimer’s Disease Reports4(1): 175–183. doi:3233/ADR-200171. PMC 7369138. PMID 32715278.
  7. Irwin MR, Vitiello MV (March 2019). “Implications of sleep disturbance and inflammation for Alzheimer’s disease dementia”. The Lancet. Neurology. 18 (3): 296–306. doi:1016/S1474-4422(18)30450-2. PMID 30661858. S2CID 58546748.
  8. Breijyeh Z, Karaman R (December 2020). “Comprehensive Review on Alzheimer’s Disease: Causes and Treatment”. Molecules (Review). 25 (24): 5789. doi:3390/molecules25245789. PMC 7764106. PMID 33302541.
  9. Knopman DS, Amieva H, Petersen RC, et al. (May 2021). “Alzheimer disease”. Nat Rev Dis Primers. 7 (1): 33. doi:1038/s41572-021-00269-y. PMC 8574196. PMID 33986301.
  10. Makhlouf S, Messelmani M, Zaouali J, Mrissa R (March 2018). “Cognitive impairment in celiac disease and non-celiac gluten sensitivity: review of literature on the main cognitive impairments, the imaging and the effect of gluten free diet”. Acta Neurologica Belgica (Review). 118 (1): 21–27. doi:1007/s13760-017-0870-z. PMID 29247390. S2CID 3943047.
  11. Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, et al. (April 2015). “Neuroinflammation in Alzheimer’s disease”. The Lancet. Neurology. 14 (4): 388–405. doi:1016/S1474-4422(15)70016-5. PMC 5909703. PMID 25792098.
  12. Gauthreaux K, Bonnett TA, Besser LM, et al. (May 2020). “Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy”. J Neuropathology Exp Neurol. 79 (5): 465–473. doi:1093/jnen/nlaa014. PMC 7160616. PMID 32186726.

DEMENTIA, Invite Health Blog

DEMENTIA, Invite Health Blog

Written by: Dr. Claire Arcidiacono, ND For further questions or concerns email me at carcidiacono@invitehealth.com† Dementia is a complex issue that concerns many people. Dementia is a complex topic because not only is it considered by many to be a neurocognitive disorder on its own, but 

The Brain, Blood Tests & More, Part 2, Invite Health Blog

The Brain, Blood Tests & More, Part 2, Invite Health Blog

Written by: Dr. Claire Arcidiacono, ND For further questions or concerns email me at carcidiacono@invitehealth.com† In our last blog we started our conversation regarding brain health talking about different conditions that you should rule out when experiencing memory changes. This week we will be delving into 

Feeling Frazzled? Get Focused! Invite Health Podcast, Episode 650

Feeling Frazzled? Get Focused! Invite Health Podcast, Episode 650

 

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Please see below for a complete transcript of this episode.

FEELING FRAZZLED? GET FOCUSED! INVITE HEALTH PODCAST, EPISODE 650

Hosted by Amanda Williams, MD, MPH.

*Intro Music*

InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed health care professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that Invite Health has to offer at www.invitehealth.com/podcast. First time customers can use promo code podcast at checkout for an additional 15% off your first purchase. Let’s get started. † [00:00:34]

*Intro Music*

Amanda Williams MD, MPH: [00:00:40] I’ve talked a lot about stress versus burnout in the past and even talked about brain fog. But we know that this is a major problem that so many Americans are dealing with every single day. So, I feel like it’s a topic that needs to be discussed in some more detail. When you look at the statistics of how many Americans are feeling incredibly stressed out and this is affecting all aspects of their life, maybe you get to work, and you feel like you’re not focused or you’re having a hard time completing task. Maybe you’re in school and you’re having a hard time meeting deadlines for certain projects that are due. So, this is an area where we know that through lifestyle modifications, we can make major gains. So, I am Dr. Amanda Williams, scientific director at Invite Health, and they did a survey across the country, and they recognized that well over 80% of workers experience what they consider to be high levels of work-related stress. Well, this is a major issue if you have basically eight out of ten individuals in any office building or in any factory or any place of employment feeling incredibly stressed out that can show what leads us down that path the burnout. Burnout used to always be looked at as something that only applied to folks who were in the health care field. We now recognize that because of our hectic lifestyles that most people are trying to tackle too many things, that stress level is really quite high, and burnout is a real thing. So, I encourage you to go back and listen to the previous podcast on, stress versus burnout so you can recognize the difference. † [00:02:25]

[00:02:26] But we can see how we can have a loss of energy, a loss of focus, a loss of attention. Just an overall sense of not feeling right, feeling as people always say, I feel stressed out. We know that there are many things that we can try to do to decompress ourselves, but not everybody’s into meditation or yoga, but there are other techniques that you can turn to, and I encourage you to find a mindfulness technique that’s going to appeal to you that you can start to apply on a regular basis when you feel those moments of stress so that you can focus on your breathing, perhaps, or take your mind to a different place, even if it’s only for two, three, four or 5 minutes, it can make an astronomical difference, in so many aspects, not only of your mental well-being but for your physical well-being as well. Because we can see the correlation between high levels of stress and cardiovascular disease, and dysregulation of our blood sugar, for example. But in particular, when most people think about stress, they feel like they feel it in their brain, and I think that this is an important takeaway is to recognize that our brain is very power in feeling that low energy or that lack of motivation. This is a clue to you that your brain is screaming for nutrients. Your brain is asking, please feed me. Kind of like if you get that rumble in your stomach and you say, Oh, I’m very hungry. Well, your brain is also hungry for key nutrients in order to be able to offset all of those daily stressors that we come across each and every single day. So, we know the importance of healthy diet and adherence to a Mediterranean diet is certainly the way that we want to proceed forward. We know that those high antioxidant foods certainly can do so much to boost our cognitive performance. † [00:04:17]

DAILY FOCUS & MEMORY SUPPORT JUST GOT EASIER, INVITE HEALTH PODCAST, EPISODE 648>>LISTEN NOW!

[00:04:18] We also recognize that healthy omega three fatty acids are incredibly important to our brain and for the functionality within the brain, a lot of people say, oh, I have ADHD, and we know that in childhood we see higher percentages of young boys and girls who are diagnosed with ADHD or attention deficit hyperactivity disorder. But this is quite common in adults as well. And when you have high percentages of Americans who have been clinically diagnosed as having ADHD, and then you have a whole another group of folks who are self-diagnosed as having ADHD, we have to zero in the real problem. We have to look at the diet. We have to look at our mechanisms that we use in order to decompress our stress. I often say that Americans stay in that lane of sympathetic overdrive and have a difficult time pumping that brake with the parasympathetic. nervous system. Now you see other places around the world where they do a much better job. They take longer vacations, they take breaks during the middle of the day, and they sit down, and they enjoy a meal. They’re not trying to power through their lunch like most Americans, if you even have the time to eat your lunch and when Americans do choose the foods, they’re getting something that’s quick grab and go ultra processed. And we wonder why our brain, when we return from lunch has a very difficult time focusing and why we start to feel sleepy because we’re not nourishing our system in the appropriate way. But we know that there are many things that we can do each and every single day to add to our supplementation routine that can zero in on supporting healthy cognition and allowing us to have better focus and attention. So, I’m going to zero in just on a couple of things today. † [00:06:11]

[00:06:11] Phosphatidylserine folks, Phostidylserine is a very important phospholipid. This is a key fat that helps to support our brain and the way that the brain is reacting and responding each and every single day, even with the release of key neurotransmitters including acetylcholine. We have seen now how the use of phostidylserine supplementation has been shown to be highly effective in both pediatric and adult cases of attention deficit hyperactivity disorder and the Journal of Alternative and Complementary Medicine. They looked at a meta-analysis of multiple clinical trials, zeroing in on the utilization of phostidylserine supplementation and the overall symptoms that people experience with ADHD. And they found through this meta-analysis of these different randomized clinical trials that phostidylserine was effective in reducing symptoms of inattention, especially in children. We have seen clearly the studies done in college students and how this can really help with that stress leading into exams. So big midterm exams or their final exams, and when they started to supplement with phostidylserine, it helped to bring that stress level down. Well, we know it’s doing this in a couple of different ways. One is, it’s very great for HPA axis, so the hypothalamus- pituitary adrenal axis. The other is it is working as this membrane fat to protect our brain cells from dings and dents, as I always like to describe them. But the more stress we have, the more prone our brain cells are to having dings and dents. So, there was a study that was done in the Journal of International Sports Nutrition where they wanted to see if they could replicate the use of phostidylserine in the setting of stress when it came to exercise and performance. So, they were looking at cognitive function before and after acute exercise. They found that when giving college aged individuals phostidylserine, giving them this for two weeks and then having them do an acute physical activity, so exercising and then they assessed their plasma cortisol levels. They were looking at testosterone levels and they could see a significant improvement in their cognitive function, both pre and post workout just through taking phostidylserine for two weeks. So, that’s pretty impressive. So, if you are going to work every day and you feel like you’re exercising your mind and you’re never getting anywhere, maybe phostidylserine is the nutrient you should be turning to. We’ve been able to see how beneficial phostidylserine is in conditions such as depression, as well as anxiety. And we know in the setting of ADHD, oftentimes we have these co-morbid conditions where individuals do feel a lot of anxiety about trying to meet deadlines or trying to finish a task at work. And so, the two often go hand-in-hand, so through the action of phostidylserine, we can help to create more of this balance throughout the system. So Phostidylserine is one thing. † [00:09:42]

ICYMI:BEING SUPPLEMENT SAVVY IN THE SUMMER, INVITE HEALTH PODCAST, EPISODE 649>>LISTEN NOW!

[00:09:42] Another formulation is cerebral care, and the Cerebral care formula contains inositol. Inositol is very important when it comes to cell-to-cell communication in the brain. So now, if your brain is kind of on a hyperactive course and it’s just kind of firing away and it doesn’t know when to stop, that’s a problem because the likelihood that the brain cells have the ability to communicate with each other at that point in time is not real high, they’re just firing away. So, we need them to be able to pause and communicate effectively and say, oh, hey, this is the task we’re trying to do. So, with the use of the cerebral care formulation, we can see where we can gain valuable ground. When it comes to the way that our brain is communicating with the rest of our body, which is very key as well, too. Because remember, if your brain is feeling fatigued, the rest of your body is also going to be feeling that level of fatigue. So, we know that diet and exercise are key. We know that adding in nutrients such as phostidylserine, and then taking it to this whole different advanced level with the addition of the cerebral care powder, which gives you that inositol, it gives you some of that phostidylserine gives you acetyl- L-carnitine to energize up your brain cells, and it gives you CDP choline, which allows you to remember the tasks that you did. Many times, when people get home from work, they go gosh, what are all the things that I did today? So, we want to have very acute short- and long-term memory, so having choline as part of the cerebral care formulation helps to enhance our cognitive function by improving upon memory. So, it’s a really easy way for individuals who do feel that heightened level of stress. We know many Americans, over 80% of Americans who are working say, yeah, I’m stressed to the max. You know, millions of Americans have been diagnosed with ADHD. So, if we want to be effective, we want to have energy, we want to be task oriented, we have to zero in on feeding the brain. And this is a really good one, two combinations of the cerebral care with that phostidylserine. Of course, you want to partner this up with a good regular exercise routine with finding a mindfulness technique that is geared towards you and also adherence to a Mediterranean diet. So those are my tips for all of you Americans who are out there and feeling slightly stressed out and not focused when it comes to your day-to-day work, when it comes to whatever you are trying to accomplish, that should get you to where you want to be. And I want to thank you so much for tuning in to the Invite Health podcast. You won’t find all of our episodes for free wherever you listen to podcasts or by visiting, invitehealth.com/podcast to make sure that you subscribe, and you leave us a review. You can follow us on Facebook, Twitter and Instagram and we will see you next time for another episode of the InViteⓇ Health Podcast. † [00:09:42]

*Exit Music*