What are adrenal glands and the connection of them to our thyroid health? To find out more on this topic read more from Dr. Claire Arcidiacono, ND blog post!
Please see below for a complete transcript of this episode.
What Is Lupus? – InViteⓇ Health Podcast, Episode 522
Hosted by Amanda Williams, MPH
InViteⓇ Health Podcast Intro: Welcome to the InViteⓇ Health Podcast, where our degreed healthcare professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that InViteⓇ Health has to offer at www.invitehealth.com/podcast. First time customers can use promo code PODCAST at checkout for an additional 15% off your first purchase. Let’s get started!
Amanda Williams, MPH:
[00:00:40] When it comes to our immune system, sometimes things can go haywire, and today I want to talk about a autoimmune condition that commonly affects women. So 9 out of 10 people who are diagnosed with lupus are women, and we know that just according to statistics, we recognize that there’s roughly about one and a half million Americans who have a form of lupus. Certainly, men can be impacted by this. Children, teenagers. But for the most part, we find that a good 90% are going to be women. Between usually the ages of 20 and 40 is when the initial diagnosis occurs with lupus. So I want to talk a little bit about what exactly lupus is and what you can be doing if you yourself have been diagnosed with this, or if you happen to have a friend, a family member, a coworker who has been diagnosed with lupus.† [00:01:43]
[00:01:43] So I’m Amanda Williams, MD, MPH, Scientific Director here at InViteⓇ Health and lupus is a incredibly detrimental systemic disease. Whenever our immune system decides that it’s going to rear its ugly head and create havoc for us, that is a big problem. And there are so many different autoimmune conditions. You can look at things such as lupus, we can look at rheumatoid arthritis, we can look at diabetes. We know that there are many different ways to which our immune system can go from being a very protective thing in our, in our body to something that can be very destructive.† [00:02:30]
[00:02:31] Now we know that lupus has a common driving force, and that is inflammation. Now when you look at lupus, this is… We usually just shorten it to lupus, but we’re talking about systemic lupus erythematosus and SLE. Now we know that when it comes to SLE, hence just lupus, we’re dealing generally with multiple areas in the body. So the skin, kidneys, heart, the entire cardiovascular system, the nervous system, connective tissue, the skeletal muscular system, as well as other areas that can be impacted because of the significant inflammation that occurs. So when people have lupus, oftentimes the way that they present and many of the complications is that there are multiple organ systems that have been impacted by this. So this puts someone with lupus at a higher risk of having a heart attack, having diabetes, having chronic kidney disease, bone loss, osteoporosis, as well as different blood disorders.† [00:03:44]
[00:03:46] We can see that there are certain areas in the country to which lupus diagnosis can be at a higher rate. So we know that there is a Vitamin D connection to lupus. So you’re going to see higher rates of lupus being diagnosed throughout the Midwest, as well as the Northeast than you do in other parts of the country, including the the west coast of the country, as well as the Southeast. So we know that Vitamin D, which remember, Vitamin D is critical to our immune system. We know that Vitamin D is definitely playing a significant role. We recognize that not only is it geographically driven, but it is also very much so race driven. And we are going to see higher rates of lupus in those who are African-American, Asian-American, Native American as well as Latina women. You see this in a much greater rate, the incidence in these women, much more than you do in Caucasians. This is an area where I think it’s commonly overlooked as a public health issue, and there are so many things that should be done and can be done to improve upon the health outcomes for anyone who is diagnosed with lupus and many of the signs and symptoms of lupus can vary from one person to the next.† [00:05:18]
[00:05:19] Now, the actual diagnosis is going to come down to serum blood levels of those autoantibodies. So looking at the antibodies in the blood. But we know that sometimes people or people present with just really extreme fatigue. They may have painful, swollen joints, muscle pain. Many times people know the famous butterfly rash, but it is a rash across the cheeks. Now, that doesn’t mean that every person who has lupus will develop that because there are different types of lupus and the different systems or organs to which lupus attacks can vary from one person to the next. For some people, they can experience it with pain in their chest when breathing. So there’s many different ways. Headaches is another one that sometimes people will present with, you know, swollen joints and headaches, and it’s like what is actually happening? And then they do the serum tests and then they can see, yes, indeed, this is a case of lupus.† [00:06:27]
[00:06:28] Now, conventional treatment for lupus is very… It can be very beneficial, but it can also come with a whole host of different side effects. So many of the anti-malarial drugs, which are antiparasitic drugs, are oftentimes prescribed to those who have lupus. Now, those come with a whole host of different side effects, including significant damage that can occur within the liver. We can definitely look at the overuse of anti-inflammatory drugs, the NSAIDs, so chronic use of NSAIDs in someone who has lupus can lead to damaging effects once again when it comes to the health of the kidneys, as well as the liver, just depending upon which NSAID someone is using.† [00:07:19]
[00:07:20] So what can be beneficial in terms of what someone with lupus can do? We know that looking at the diet, making sure that we’re not adding insult to injury by having a pro-inflammatory diet foods that are going to drive up even more inflammation, so you want to have an anti-inflammatory diet. Fruits and vegetables. High antioxidant foods. Healthy fats. Things that are going to help to lower your inflammatory burden. Understanding how much stress plays a role into this. Remember, stress will drive inflammation as well. So management of stress, whether this is, you know, finding ways to do meditation or yoga or exercise, all of these make a big difference.† [00:08:08]
[00:08:10] And then we have to look at different natural interventions. Knowing that Vitamin D is directly linked to this… If you look at people who have lupus and you test their serum Vitamin D levels, you are likely to find significant insufficiency and even deficient Vitamin D levels. But we can also look at how Vitamin E, you know, inadequate Vitamin E intake can be another driving factor for this inflammation that drives up in the system. We can look at how omega-3s, so by incorporating in fish oil or krill oil, how beneficial this can be for easing inflammation. Of course, we can look at hormonal pathways, and they’ve been able to show… There’s a very important adrenal hormone known as DHEA, and low levels of DHEA have been observed in patients who have lupus, as well as other inflammatory diseases. So oftentimes you will find doctors who will prescribe DHEA to help to improve upon the health of those who have these inflammatory autoimmune conditions.† [00:09:27]
[00:09:28] So lupus itself, we know it’s a systemic autoimmune disease driven by inflammation, so the immune system is attacking tissues in the body. We know that when it comes to which system is going to be affected most, this is going to vary from one person to the next. We know that there are different types of lupus. You have SLE, which is systemic lupus, meaning that this is affecting multiple systems in the body. You have discoid lupus. Now this is… Generally speaking, discoid lupus is only affecting the skin. Then you have drug-induced lupus. So this is when you were on a particular medication that then triggers an autoimmune response. There are different drugs that are frequently associated with creating this drug-induced lupus. So this can be many of the cardiovascular drugs antiarrhythmic drugs, hydralazine, which is a blood pressure lowering drug. So we can see how it is that lupus can present in different ways for different people.† [00:10:42]
[00:10:43] But at the end of the day, what we need to do is make sure that we are doing everything in our power to lower that inflammatory burden in the system. So we want to make sure that when it comes to the dietary intake that you are adhering to an anti-inflammatory diet so that Mediterranean diet really comes into play. We know that we don’t want to have to continuously turn to the anti-malarial drugs and the high dose NSAIDs in order to try to regulate this. So we want to try and help our immune system out ourselves by giving the immune system adequate nutrients, key vitamins and minerals. Those omega-3 fatty acids that we know are so key. So Vitamin D is going to be the number one thing that you look at. We know that when it comes to lupus, deficiency of Vitamin D is going to be incredibly high. And if someone with lupus doesn’t have Vitamin D deficiency, it’s pretty much guarantee that they will have insufficiency, meaning low levels, but not to the level of complete deficiency. So having your serum 25-hydroxyvitamin D level tested is incredibly important so that you’re supplementing with the right amount of Vitamin D every day to get you back into a healthy range to once again help to regulate the immune system response. Remember, when you’re taking Vitamin D, it’s always advantageous to take magnesium to help with that proper absorption. We want to incorporate in our fish oil or krill oil, or if you want to use the vegetarian option, using flaxseed. I always encourage anyone who has been diagnosed with lupus to incorporate Vitamin E. We know that Vitamin E certainly plays a essential role in terms of stabilizing cellular membranes. So we want to make sure that those immune cells have that support, and we know that Vitamin E certainly can block that autoimmune attack just through that action of stabilizing the cell membrane. They’ve done studies where they’ve shown how Vitamin D supplementation can actually reduce the level of autoantibodies in lupus patients.† [00:13:22]
[00:13:23] We have to look at other herbal extracts. There have been many studies done with curcumin and understanding that the bioactive components those curcuminoids can do a wonderful job in terms of easing that inflammation through targeting and suppressing or lowering different cytokines that are directly linked with lupus. So looking at things like different interleukins and tumor necrosis factor alpha. We can look at the clinical trials where they’ve given curcumin extract to patients with lupus, and they can start to see an improvement across all different markers, including those who have significant impact to their kidneys. Remember, lupus is going to attack multiple organ systems. When it attacks the kidneys and creates kidney disease because of lupus, so you get nephritis, so inflammation within the kidney, they can see how it is that that curcumin can help to stabilize that kidney function. So a lot of different things that we can be looking at. We can look at that hormonal component. And if your DHEA levels are low, then looking at supplementation with DHEA can help to create that balance once again within that adrenal stress response, but at the same time helping to heighten the body’s immune system, so it’s not going into this self-destructive mode. So lupus is something that you definitely want to make sure that if you know someone, if you, you yourself have lupus, that you take action in terms of diet, exercise and proper supplementation to have a better management of this autoimmune condition.† [00:15:21]
[00:15:22] So that’s all that I have for you for today. I want to thank you so much for tuning in to the InViteⓇ Health Podcast. Remember, you can find all of our episodes for free wherever you listen to podcasts or by visiting invitehealth.com/podcast. Now do make sure that you subscribe and you leave us a review. You can follow us on Facebook, Twitter and Instagram @invitehealth and we will see you next time for another episode of the InViteⓇ Health Podcast.† [00:15:22]
The body needs sleep to recover, but issues such as stress may prevent you from getting good quality rest. Turn to Tranquil Tx, a liquid mixture of ingredients that have been clinically studied for their calming effects.
Burnout syndrome is extremely common, but the good news is that there are nutrients that can help your body adapt to the stress. Learn about how things like omega-3 fatty acids and CoQ10 can be beneficial.
Please see below for a complete transcript of this episode.
Stress Versus Burnout, Part 1 – InViteⓇ Health Podcast, Episode 502
Hosted by Amanda Williams, MPH
InVite Health Podcast Intro: Welcome to the InViteⓇ Health Podcast, where our degreed healthcare professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that InViteⓇ Health has to offer at www.invitehealth.com/podcast. First time customers can use promo code PODCAST at checkout for an additional 15% off your first purchase. Let’s get started!
Amanda Williams, MPH: [00:00:40] We’ve all said it from time to time, and that is, “I am so stressed out,” or “Oh, I feel burned out.” Today, I want to talk about the difference between stress and burnout because there is a distinct difference and understanding that is key in terms of being able to manage it. And in Part 2, I’m going to talk about nutrients that can be incredibly supportive when it comes to enhancing your energy and giving you that sense of just wanting to get out there and get back to life and do the things that you enjoy doing. So I’m Amanda Williams, MD, MPH, and let’s get right to it.† [00:01:15]
[00:01:16] Let’s talk about the actual difference between stress and burnout, because the two often go hand-in-hand. And one thing that we do know is that when it comes to stress, uncontrolled stress or chronic stress… It’s one thing to have acute stress. This is when you get startled or you can have eustress, which is actually good stress. Maybe you’re nervous a little bit to get on a rollercoaster. And so that would be a sense of you stress. So it’s not bad stress. And so some stress is actually good. Chronic stress, on the other hand, completely different. It’s kind of like when we look at the difference between acute inflammation and chronic inflammation. We know that acute inflammation is good. It helps our body heal and recover. But chronic inflammation is detrimental to our health. It’s the same thing when we look at stress and everyone has probably heard of this.† [00:02:13]
[00:02:14] They’ve actually done multiple studies to assess the level of burnout in people who work. And when you look at the statistics, it’s really incredibly alarming. I’ve done many presentations on stress and burnout through the years and presented to medical students, so they have a better awareness of why they need to be cognizant of the difference. And when you traverse over from stress into burnout, why that’s so detrimental. Because in healthcare in particular, you see a much greater likelihood of developing burnout than from other occupations. Clearly, it’s across all occupations, but we do see that in medicine in particular, it is a really alarmingly high rate and there’s a reason for this. And part of that is because the burnout phase starts in the education process. So starting in medical schools where most people start to go from that stress into the burnout category, and this is where the problem starts to present itself in terms of the long term implications.† [00:03:26]
[00:03:28] So I’ve talked about stress before in different podcasts and how we can go about trying to manage our stress. And as I mentioned in Part 2, I’ll go into different nutrients, but trying to differentiate between the two… When we think about being stressed out, this is when, you know, where emotions are very strong towards something like you really have a lot of care, I guess is one way to put it, put it into perspective. Where you feel very anxious and you feel kind of hyperactive, like, “Oh, I’m so stressed out, I have to race over here and I have to do this.” That is much different than burnout. Burnout is when you feel drained. You don’t, you no longer have that hyperactive component that’s driving you. You feel helpless. So you go from that anxious feeling to just feeling completely run down. And just, “What do I do?” And so you can see, even just from that example, that there is a clear distinction between the two.† [00:04:35]
[00:04:35] We know with stress, oftentimes we feel this in a more physical sense, where maybe your stomach, it’s, you know, people say, “Oh, my stomach’s in a knot.” Maybe you feel a little bit jittery. Maybe you feel like you’re sweating a little bit. When we look at burnout, we transition more over into that emotional component. So there’s also the physical that’s there because remember, we have the low-energy state, so you just feel completely drained. But it’s that emotional toll that really builds up when you have burnout, in a way, you almost have like this blunted emotional response. So when you’re stressed and someone says, “Oh, I need you to do this and I need you to do it right now,” you get yourself worked up and go, “Oh my gosh, how am I going to? I can’t do all of this.” So you’re still having this emotional attachment to it.† [00:05:24]
[00:05:25] When you are burned out, you have, in a sense, kind of checked out. And it’s key, too, to understand this because we know that there is clearly a problem. And with every problem, we know that there are solutions and we don’t want to get ourselves to the point where the stress becomes so unmanageable that we do get burned out because once you’re at burnout, it’s very difficult. So we can kind of look at having a container or our coping reserve. We can have positive inputs into that coping reserve. We can have negative inputs into that coping reserve. In the outcome of trying to get that balance between the negative and the positive is what can dictate if we get burned out or if we can remain resilient, even under stress. So there are a lot of different factors that we have to consider, you know, positive input, such as having a good support system, having a good social life. Having a healthy diet, having someone who maybe mentors you, even in the setting of learning a new task at work, which can be stressful, but if you have someone who’s there and mentoring you, this can make all the difference. When we look at the negative inputs, you know, the stress building and mounting and mounting and having our own internal conflicts of, “Can I do this? Can I take all of this on?” This is when that coping reserve can get incredibly imbalanced. And then you start to see the signs of burnout, a sense of failure. You have a lot more self-doubt. You feel helpless. You feel defeated in many cases. Many times people start to withdraw. You become detached from your normal social setting. You have a loss of motivation. Maybe you become incredibly negative and you think, “I used to always be such a positive person and now I’m incredibly pessimistic. It doesn’t matter what it is, I just have a negative attitude towards it.” And this is a bad thing. And then we can look at even when you do accomplish something that you’re like, eh, and you just have no sense of satisfaction in that. Maybe you find that you are very irritable. Maybe your sleep patterns have become incredibly disrupted. Perhaps you’re sleeping more than you used to. Or maybe you can’t sleep at all. You can become very apathetic. You may start to have signs of different emotional breakdowns.† [00:08:10]
[00:08:11] And these are all things that we need to be aware of, because when they do studies and they say nearly 8 out of every 10 workers experience burnout at some point in their lives, then that’s a big problem. When they did a recent study looking at employee burnout, they surveyed over a thousand respondents, 77% of those said that they’ve experienced burnout at their current position. 91% that, said that the unmanageable stress or frustration impacts the quality of their work. And 83% of them said that burn out negatively affects personal relationships. So even those who they had in the survey that said, “Yeah, I’m still passionate about what I do, I still like what I do,” the 64 of them said “I’m still stressed out.” 64% of them still said, “I’m incredibly stressed out.” I’ve seen this in numerous studies in physicians where they have assessed, the Mayo Clinic has assessed physicians and 88% of doctors… This was years ago. Now you add the pandemic into it, but 88% of doctors, and this is probably 2015 that they assessed, said, “Yeah, I’m moderately to severely stressed.” Over 50% of them said, “Yeah, I think I could classify myself as being burned out.” So we know that this is prevalent.† [00:09:50]
[00:09:51] We know that the World Health Organization has defined burnout as a syndrome resulting from workplace stress that has not been successfully managed. So what are we talking about? Acute stress that then becomes chronic stress that then becomes unmanageable stress that then becomes burnout. So then we have these feelings of energy depletion. We feel exhausted. We have this distancing from our emotions. And I said many people withdraw from social interactions. We know that when they’ve done work and wellbeing surveys, 80% of American workers who were assessed said they experienced work-related stress. I wanted to bring this up because I have a lot of people who reach out to me and ask, “You know, I feel stressed out or I have a lot going on right now and I’m taking care of this person, plus I’m working, I’m trying to go to school.” I mean, people sometimes put a lot on themselves. And trying to find ways to cope with that. Remember, we have our coping reserve. It’s creating that balance. We’re always going to have stress. There’s always going to be a certain amount of stressors that we have absolutely no control over, but it’s how we react to those stressors, how we manage that stress to prevent us from falling into that category of being burned out.† [00:11:32]
[00:11:33] And I myself have been in that position. I remember many years ago, you know, finishing medical school, working on my master’s degree in public health. I got to the point where I was technically burned out. I felt like my brain was like Play-Doh, like you could do as you wish with it because it didn’t matter to me anymore. And that’s a really bad place to be. And so through many different modifications in terms of my lifestyle, in terms of, you know, what I eat every day, the nutrients that I take in, being mindful, have made all the difference, that even in the setting of having to multitask and do all of these different things, I’m able to manage it. But we have to be cognizant, we can’t just accept it and say, “Well, I’m just stressed out and this is how it is.” No, you’re going to have stress, but having enough recognition for that stress, because remember, sometimes we think, “Well, maybe someone higher up is going to notice that I’m stressed out.” They’re not because they are stressed out themselves, even though from your, you know, point of view, you may not look and see that they’re stressed. But everyone has stress. So it’s identifying it in ourselves and then saying, “What can I do about this? Because I’m obviously, you know, I’m not going to change my job. I can’t change my job, which is the position that many workers are in. So how do I manage this better? What can I do to not allow myself to become withdrawn and to start to have this apathy towards everything? I have less motivation feeling drained.” Having a difficult time to put any type of effort into what you’re trying to do every day. And it matters to your overall longevity. At the end of the day, it truly does. We can see the, not only the mental health toll that this has, but the physiological effect of burnout. When it comes to the cardiovascular system, when it comes to our cognitive abilities, so we need to reconnect. And in Part 2, that’s what I’m going to talk about. What are things that we can be doing to better support all of the different stressors in our life to try and stop burnout from occurring? So that will be covered in Part 2. So do make sure that you tune in and listen to that.† [00:14:23]
[00:14:23] I want to thank you so much for listening to the InViteⓇ Health Podcast. You can find all of our episodes for free wherever you listen to podcasts or by visiting invitehealth.com/podcast. Do make sure that you subscribe and you leave us a review. You can follow us on Facebook, Twitter and Instagram. And we will see you next time for another episode of the InViteⓇ Health Podcast.† [00:14:23]