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CoQ10 Ubiquinol and Selenium: You Need These for Stroke Or Heart Attacks – InVite Health Podcast Episode 555
Please see below for a complete transcript of this episode.
CoQ10 Ubiquinol and Selenium: You Need These for Stroke Or Heart Attacks – InViteⓇ Health Podcast Episode 555
Hosted by Jerry Hickey, Ph.
InViteⓇ Health Podcast Intro: Welcome to the InViteⓇ Health Podcast, where our degreed healthcare professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that InViteⓇ Health has to offer at www.invitehealth.com/podcast. First time customers can use promo code PODCAST at checkout for an additional 15% off your first purchase. Let’s get started!†
Jerry Hickey, Ph.: [00:00:40] Coenzyme Q10 is an extremely well known supplement, and it’s really very safe and it’s incredibly beneficial. It was first discovered in Japan at the turn of the 20th century, and the research has been mounting ever since. A great deal of research comes from Texas, where a lot of the work was performed. In fact, the CoQ10 we use, the active form Ubiquinol actually comes from Texas and it’s been found to be core to metabolism. It’s at the core of producing energy from all foods, fats, carbohydrates, proteins. It affects our ability to create energy. Now for coenzyme Q10 to have this effect and of course, that’s natural to the human body. It has to be converted into a different form in your body. So the CoQ10 that most people buy in a health food store or pharmacy has to be changed before it works, before it benefits you. This active form is called Ubiquinol. Now there’s very strong evidence that it truly helps protect you if you suffered previously with a heart attack or a stroke, or if you suffer with heart failure. It’s the Ubiquinol form that will offer the best level of protection. And here’s the issue. Many people fail to adequately convert classical CoQ10 supplements to Ubiquinol, so they would be far better off if they switched to a Ubiquinol supplement.† [00:02:23]
[00:02:25] So welcome to my episode. Take the supplement if you’ve had a stroke or a heart attack. Hi, my name is Jerry Hickey, I’m a nutritional pharmacist, I’m a licensed pharmacist. I’ve been doing this for many decades. Welcome to the episode. You can find all of our episodes for free wherever you listen to podcasts or just go to invitehealth.com/podcast we have hundreds and hundreds of InViteⓇ has hundreds and hundreds of episodes. You can also find us on Instagram, Twitter and Facebook at InViteⓇ Health and of course, please subscribe and leave us a review.† [00:03:00]
[00:03:02] Now there’s different forms of stroke. The most common stroke is an ischemic stroke where something blocked the flow of blood in the brain and parts of the brain can die and are supplements that have some utility in helping lower the risk of a stroke. The biggest cause of a stroke is high blood pressure. The second leading cause is an arrhythmia of the heart. An arrhythmia means improper beating pattern. The heart has to be it has to have a dependable, normal beating pattern. But in atrial fibrillation, second most common cause of a stroke, the top chambers of the heart are fluttering. And there’s all kinds of crazy patterns skip beats, triple beats, etc. The heart’s racing, and what happens are little red blood cells get left behind and clotting factors can adhere to them. And eventually they shoot out of the heart, can go into the brain and cause a stroke. So after a stroke, Ubiquinol really becomes quite important. This is the Journal of Molecular Neuroscience. Neuroscience, of course, is the brain is a number of studies of Ubiquinol with the brain in children and adults, neuromuscular studies, brain studies.† [00:04:21]
[00:04:21] So this is a large group of stroke patients. And what they did within less than 24 hours, they measured the level of two nutrients in their blood. SOD which stands for superoxide dismutase a major antioxidant enzyme that defends your brain. SOD levels tend to crash and burn after the age of 55. They’re pretty much very low in everybody after the age of 65 and Ubiquinol, which also drops in your heart, your brain and your muscles, etc., with age. So these are two major protective factors. So they found in people who suffered a stroke when they measured within the first 24 hours there was a really big drop in SOD and a really big drop in the level of Ubiquinol. And they found a correlation over time between the level of damage from the stroke and a drop in these two nutrients. And they also found a correlation between reduced mental function after a stroke like six months later and the catastrophic drop in SOD and Ubiquinol.† [00:05:22]
[00:05:26] Now the left side of your heart pumps out oxygen, rich blood to the body. To do this, it passes through a valve leading to the biggest blood vessel in the body, the abdominal aortic artery. The valve is called the aortic valve, so blood is pumped from the left, lower chamber, the heart. It goes through this valve aortic valve and enters the aorta, which brings in blood all over the body. So you get oxygen and nutrition. So the valve allows blood to be pumped out of the heart, but prevents backflow of the blood it prevents the blood from reentering the heart inappropriately.† [00:06:05]
[00:06:08] There’s a condition called aortic stenosis. The valve is narrowed and has different levels and symptoms when you truly have some level of aortic stenosis. You can have severe fatigue and tiredness after exertion, shortness of breath, chest pain. Other things can happen like arrhythmias, so it can lead to strokes, arrhythmias, heart failure. The age of patients with aortic stenosis is rising. People are living longer. And unfortunately, this compromises things like the level of benefit from the surgery is reduced. There’s more complications in these people. There’s poorer outcomes. There’s reduced heart performance. So there was an Italian study published in the journal Aging. The Journal Aging is published up in Albany, New York, and 50 elderly patients with severe aortic stenosis. They were going to undergo surgery for aortic valve replacement. They gave them Ubiquinol or placebo, Ubiquinol prevented an increase and troponin one after the surgery. That’s really important, troponin one is found inside the cells of the heart and wonder damaged it leaks out of the heart. So there’s a rise in troponin one that signifies the amount of damage to the heart. There’s a correlation there. In fact, after a heart attack or a suspected heart attack, doctors will check the blood for Troponin one. And if they see it’s elevated, they know that the person had a heart attack. So the Ubiquinol prevented an increase in troponin one, meaning that it was preventing damage to the heart cells of the heart muscle. The heart was stronger after the surgery on Ubiquinol with improved health versus no Ubiquinol. So the strength of the heart was improved and the risk of suffering with congestive heart failure or an arrhythmia, you know, an improper beating pattern which can lead to a stroke or stiffening of the heart, fibrosis of the heart. The risk of all of these was decreased and so was inflammation in the heart. So it’s all very good.† [00:08:29]
[00:08:30] But let’s look at heart attacks. Heart attacks typically occur when something blocks the flow of blood in the heart and part of the heart muscle dies. And one of the outcomes of a heart attack, besides arrhythmias, is heart failure, where the heart stiffens and enlarges and it becomes increasingly hard for the heart to pump blood. So this is the Journal of Cardiovascular Antiracist Research, and the researchers looked at quality of life and 128 patients after they suffered with a true heart attack, not a minor heart attack, a real heart attack. Now, they were on the best drugs that medicine has to offer, like beta blockers and ACE inhibitors and ARBs, aldosterone blocking drugs like tryptamine. The lucky patients were placed on a better diet and the researchers focused on raising their plasma levels of Ubiquinol and L-carnitine through supplementation. So Ubiquinol allows you to create energy in the heart and in your muscles and in all of your organs and tissues throughout your body, carnitine is similar. Carnitine feeds your cells of your heart, in your brain, etc., with the precursor for creating energy out of food. So they’re both very important after a heart attack. Ubiquinol and L-carnitine. Now through the supplementation compared to the other groups, because some of them were not placed on diet, some of them were not placed on the supplements compared to the other groups supplementation increased the quality of life. They had a lot more energy, they had an improved mood, their emotions improved, but their prognosis also improved. The doctor said, Hey, you’re going to do a lot better with the better diet and Ubiquinol and the carnitine than if you didn’t have these supplements and a better diet.† [00:10:30]
[00:10:31] Now, this one is really telling heart failure is very scary. They classify heart failure, according to the New York Heart Association classification stage one. Hey, you don’t even know you have heart failure. Stage two. You probably have a little trouble breathing and you’re probably fatigued after exercise or physical activity. Stage three Heart failure. You’re experiencing the symptoms just sitting in a chair and you’re just sitting on the couch watching TV and it’s hard to breathe and you’re fatigued. Stage four is really scary. Stage four Heart failure is more scary than HIV because people with HIV infections are now put on a cocktail of drugs that keeps them alive. Stage four Heart failure is as scary as advanced cancer, and it has a very poor prognosis and a short time. I mean, it’s just not it’s just not a good thing. So all of the patients, it’s a Danish front study, 420 patients with severe heart failure. So the New York Heart Association classification was stage three or four. So it’s not good. And they were already on the best medications, like the beta blockers, like the ARBs, like ACE inhibitors. They were supplemented to increase the Ubiquinol levels or given placebo.† [00:11:47]
[00:11:49] Here’s the results they were they were amazing. It was over a two year period for people with class three and class four heart failure two years is a very long time. A 43. With the Ubiquinol 43% reduction in cardiovascular related deaths. In other words, a death from a heart attack or an arrhythmia like ventricular tachycardia where the lower left chambers racing or sudden cardiac death. So a 43% reduction in dying, a 42% reduced risk of dying from all cause mortality. So that could be anything including infections. Because don’t forget, these people, their immune system compromised it’s not working well so it’s easy for them to get infections, even heart infections. The nt probnp significantly improved now that’s important. Nt probnp is a protein found in the cells of the heart and cardio cardiologists. An interventional cardiologist will look at the level of nt probnp in the blood to see how damaged the heart is, where if their medication is improving this patient’s health. So when you have a heart attack and heart failure, nt probnp is leaking out of heart and the level in the blood rises. They found a level of nt probnp significantly improved, significantly dropped. And I have to tell you, this other study showing this where they gave older people Ubiquinol versus regular CoQ10 versus placebo and only the Ubiquinol improved nt probnp in older people. Hospitalizations were greatly reduced. The need for a heart transplant was greatly reduced. The need for being put on a mechanical pump to help the heart work was greatly reduced. So there’s a lot going on here.† [00:13:34]
[00:13:36] So in the American Journal of Cardiovascular Drugs, this is a Japanese study. Patients with stable heart failure. Stable heart failure is safer than unstable heart failure, obviously, but they had a reduced ejection fraction. So that’s really important. The heart is just not pumping enough blood to meet their needs. So they’re not getting enough oxygen and nutrition to the brain and their organs and system. Not a good thing, fatigue, hard to breathe, I mean, a lot of symptoms here. They were placed on Ubiquinol or placebo, and the Ubiquinol greatly improved the function of their endothelial tissues. Now, that’s really important. Endothelial tissues line your blood vessels like a rug. The cells line your blood vessels like rug shoulder to shoulder, and they pump up in your blood vessels. So this is a reason why they were less likely to wind up in the hospital or have a second heart attack or wind up for heart transplant. It’s over because everything was working better for their circulation.† [00:14:36]
[00:14:39] Now there’s a lot to say about Ubiquinol. I mention a study on my radio program many times that took place in Sweden Linköping University, great research institution, the Karolinska Institute, another great research institution, and they gave elderly people supplements to raise their Ubiquinol level, but also to restore their selenium level. Selenium is a mineral that’s involved with reducing the risk of certain cancers if you utilize it properly, not everybody useful utilizes it properly. It’s also needed for the health of the liver and the eyes and the brain, and also for the health of the heart. So to make everything fair, they had to give everybody selenium because they want see that Ubiquinol make a difference. Everybody was given selenium. Now, Ubiquinol when they gave these very elderly everybody who was over 60 some of these people were in their eighties. When they gave these elderly people the supplements it reduced their risk of dying from heart related events by over 50%, such as a heart attack and arrhythmia, a heart failure, sudden cardiac death, or reduced. Now, they went back and looked at these patients ten years later. So these patients were put on the supplements for five years and then it stopped and they revisited these patients ten years later and 12 years later, they found that there had been long lasting benefits for from restoring the selenium and giving the patients Ubiquinol. 12 years later, they still had a 40% lower risk of dying from something related to the heart, such as a heart attack or a stroke or sudden cardiac cardiac death. I mean, it shows that even for a limited time, if you took Ubiquinol daily for five years, it just turn back the clock on your heart health and your heart remained younger than your chronological health. So if you were 70 and you took ubiquinol when all of a sudden you had a 50 year old heart, 50 year old heart don’t normally have a heart attack. So when you’re 80, you still had a 60 year old heart. It’s kind of like that. I mean, you can’t directly quantify it, qualify it, but the heart was made younger. So I think anybody over the age of like 55 or 60 really should be on kaneka Ubiquinol and I would take 120 milligrams a day would food. But if you have damage to the heart or if you’ve suffered with a stroke or heart attack, you want to take more. So discuss that with your nutritionist or your doctor or pharmacist. But certainly 240 to 400 milligrams a day would have a significant effect on improving your health.† [00:17:13]
[00:17:14] There are other supplements that could be beneficial after a stroke or heart attack. Of course you should discuss all of this what your health care professionals besides Ubiquinol and the brain it could be Alcar, a form of carnitine that gets into the brain and the heart it could be carnitine. B Vitamins are very important to both the brain and the heart. B Vitamins because they allow you to use calories for energy, especially B6, B12, folate and riboflavin. The mineral magnesium can be very helpful. All of these have benefit after a heart attack, but once again, you need guidance on this. So I want to thank you for listening to today’s episode. You can find all of our episodes for free wherever you listen to your podcasts, or just go to invitehealth.com/ podcast. You can also listen InViteⓇ on Twitter and Instagram and Facebook at InViteⓇ Health. And by the way, when you listen to our podcast, if you could leave a a review and if you could subscribe I’ll be very helpful, gives us feedback, reviews. And I want to thank you for listening to today’s episode. And this is Jerry Hickey signing off. Thank you.† [00:17:14]
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Please see below for a complete transcript of this episode.
HbA1C: Why It Matters to Healthy Aging – InViteⓇ Health Podcast, Episode 515
Hosted by Amanda Williams, MPH
InViteⓇ Health Podcast Intro: Welcome to the InViteⓇ Health Podcast, where our degreed healthcare professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that InViteⓇ Health has to offer at www.invitehealth.com/podcast. First time customers can use promo code PODCAST at checkout for an additional 15% off your first purchase. Let’s get started!
Amanda Williams, MPH:
[00:00:40] Why you should test your Hemoglobin A1C level on an annual basis is really important. Oftentimes, when we think about HbA1c, we think in the setting of diabetes. And of course, this is the key indicator for the measuring and monitoring of diabetics. But it’s also very important that we know if we are prediabetic or if our Hemoglobin A1C level is in a good and healthy range. So today I want to talk about what exactly HbA1c is and some different nutrients that can be very beneficial when it comes to targeting glycation.† [00:01:10]
[00:01:11] I’m Amanda Williams, MD, MPH and Hemoglobin A1C is a marker that we assess when it comes to the management of your blood sugar and Hemoglobin A1C is basically measuring the amount of blood sugar that’s attached to hemoglobin. And when we think about glycation, I’ve mentioned this on many different shows and podcasts before, why glycation and advanced glycation end products are so detrimental. So we know that every time that we eat, we are going to get a rise in blood sugar, blood glucose. And this is irrelevant if someone’s a diabetic or not a diabetic, your blood sugar is going to go up. What happens is that if we get this rise in advanced glycation end products, this can do significant damage. So when you understand that these glycation products actually hook on to things such as proteins, and we’re thinking hemoglobin, which is a protein, and this is an indication that damage is being done at the level of our red blood cell. We’re thinking about Hemoglobin A1C. What we know about advanced glycation end products is that they deactivate enzymes, they disrupt cell signaling pathways. They certainly can damage our cellular DNA. They can drive up inflammation and oxidative stress, all of things that are incredibly problematic for our body.† [00:02:37]
[00:02:38] So we think about Hemoglobin A1C. What we’re actually looking for is the rate of glycation, those advanced glycation end products that are actually attaching to your red blood cell. Now, understanding that red blood cells have a lifespan of 120 days. So when you assess Hemoglobin A1C, this is exactly what we’re looking at. We’re looking at the rate of glycation that occurs over the course of that three months, which is why it’s a much better test to run than, say, if you were to just test your fasting glucose. Fasting glucose is a snapshot in time, it’s telling you what’s happening right now, but it doesn’t give us a clear indication of how much of that elevated glucose is actually going to convert into those advanced glycation end products and wreak havoc when it comes to our hemoglobin. So when assessing for prediabetes and diabetes, Hemoglobin A1C is always the go to. If that level is high, that indicates that there is a high level of glycation that is occurring. And this is problematic not just because it shows that we’ve got significant insulin resistance and the body is having a hard time managing glucose. But we know that this is going to impact every other organ system in the body. So when you think about your heart, when you think about your kidneys, when you think about the nervous system, we know that those AGEs, as they are known, will create a lot of bad things for us.† [00:04:02]
[00:04:03] Now, when you look at the rates or the levels, I should say, what those actually mean. So say you go in and you have a Hemoglobin A1C test done. What you’re looking for, ideally according to most labs, is a Hemoglobin A1C level at 5.7 or below. I look at that to be even lower. I think it should be 5.5 or lower. You’re considered a prediabetic when your hemoglobin A1C level is coming back at 5.7 To 6.4. Now, once you reach a Hemoglobin A1C level that is above a 6.5, now you are categorized or diagnosed as being a diabetic. Now I have seen Hemoglobin A1C levels in the teens, 15, 16 20, and that is incredibly alarming if you see a level that high because you now recognize that that glycation has gone well outside of just your hemoglobin and this is now likely to be hitting up your nervous system in a significant manner. You know, really creating havoc within your vascular system. So the evaluation of Hemoglobin A1C in terms of long term blood sugar control is one of the most important things that we can assess, not only in the setting of just blood glucose regulation, but when we think about our aging process. And I always say we want to age gracefully if we’re walking around with high levels of advanced glycation end products that are damaging certain areas of the body, we need to be aware of this so we can make corrections to our lifestyle when it comes to diet, when it comes to exercise and obviously when it comes to the nutrients that you are taking in.† [00:05:39]
[00:05:39] So Hemoglobin A1C, commonly tested in diabetics, we know that, you know, if you go in to your doctor, they’re not just going to generally run a Hemoglobin A1C unless they have a suspicion that you are a diabetic. The problem is, is that we know there are so many prediabetics in this country. At the last estimate, it was around 80 million people who are actually prediabetic, meaning that that Hemoglobin A1C level is testing back at 5.7 to 6.4. That’s a problem because if you, say you’re wavering at 5.6, you need to be making those corrections. You don’t want to wait until the level of glycation damage is such that you are now technically a prediabetic or a full blown diabetic. So it’s very important. This is why when doctors assess Hemoglobin A1C, they always say this gives us an look at how well your average blood sugar levels have been running over the course of the past two to three months. Because remember, what we’re looking at is that life span of a red blood cell. So in general, that’s kind of the way that it is looked at. Remember, hemoglobin is a protein, and we know that those advanced glycation end products love to attach to proteins. So this is why this is a very accurate test to do.† [00:06:52]
[00:06:53] So say, for example, your hemoglobin A1C is not technically putting you at a prediabetic or a diabetic, but it’s still higher than you would like to see. So maybe you’re at 5.6, then what should you be doing? Or let’s just say you’re in that prediabetic range or even the diabetic range? What should you be doing? Well, we want to make sure that we’re taking nutrients that we know are very geared towards targeting advanced glycation end products with the regulation of blood glucose and enhancing the insulin sensitivity. So this is where Nerve HxⓇ becomes your new best friend because this is a fat-soluble form of Vitamin B1. And what’s really unique about this fat-soluble B1? So remember, all of our B-vitamins are water-soluble, so this is very unique in and of itself that it is of a fat-soluble variety. But we know that it does something really important, which is the activation of an enzyme called transketolase. Now, transketolase helps our body convert these toxic glucose metabolites into harmless or neutral compounds so that the body can then manage them so they’re not converting into these AGEs or advanced glycation end products. So this is why Nerve HxⓇ containing the benfotiamine is certainly one of the little weapons in your arsenal.† [00:08:10]
[00:08:11] But I would also look towards other nutrients that we know are incredibly beneficial when it comes to targeting AGEs or glycation in the body. And that would include things such as Alcar with ALA. We certainly understand the important multimodal functions of alpha lipoic acid in the body, and when it comes to the way that alpha lipoic acid can help the body with that regulation of those glycation and products. So Nerve HxⓇ is a first and foremost, then we also want to look at Alcar with ALA. We want to make sure that we are changing our diet, that we are not creating these major spikes in blood sugar. So adherence to a Mediterranean diet is certainly important. Getting adequate exercise, even if it’s, you know, 20, 30 minutes a day of just light walking can make an impact on how your body is managing your blood glucose. So this is also key.† [00:09:05]
[00:09:05] And then we can look at formulations such as the Gluco HxⓇ, which you would take about 15 minutes prior to meals. This is a combination of key minerals, trace minerals such as chromium and vanadium that help to wake up your insulin, along with extracts such as bitter melon, which have been shown in human clinical trials to be incredibly powerful at promoting the wakefulness of our insulin. And this is always important. We want to make sure that insulin can respond to those big increases in glucose, so it helps to push that down, so we are less likely to allow our body to make those advanced glycation end products. So Hemoglobin A1C certainly is a test that would be advantageous to request your doctor to to run, even if you don’t have those concerns of being a diabetic or prediabetic. It certainly can give you a lot of insight as to how while your body is managing those advanced glycation and products and it gives you that open door to be able to make those modifications based off of where that level is. So definitely next time you go in and you have your blood work done, check out Hemoglobin A1C, make sure that you test that. If you have issues, you know the nutrients that you can turn to to give you some additional support.† [00:10:17]
[00:10:18] I want to thank you so much for tuning in to the InViteⓇ Health Podcast. Remember, you can listen to all of our episodes for free wherever you listen to podcasts, make sure that you subscribe and leave us a review. You can follow us on Facebook, Twitter and Instagram. We will see you next time for another episode of the InViteⓇ Health Podcast.† [00:10:18]