What You Need To Know About Gout – InVite Health Podcast, Episode 309
Gout is an incredibly painful form of arthritis. But what can exacerbate it and what should you be doing to better manage it?
Tag: inflammation
Clinically Studied Strains Of Bacteria to Support Overall Health – InVite Health Podcast, Episode 288
Not all probiotics are created equal! It’s important to understand the quality and purity behind your probiotic formulation. Here’s what you need to know about beneficial bacteria.
SAMe Benefits More Than Just Your Mood – InVite Health Podcast, Episode 287
same
Invite Health Podcast, Episode hosted by Amanda Williams, MPH.
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What in the world is SAMe? This is a question that comes up often when people talk about taking different supplements, especially in relation to mood. I want to tell you all about SAMe and what it is actually doing in the body. If you are just thinking of SAMe to try to promote a healthier state of mind, certainly that’s a great thing, but I also want you to know more about what SAMe can actually do for your overall health.
What is SAMe?
SAMe was first discovered in 1952. It’s an endogenous (naturally occurring) intracellular amino acid metabolite and enzyme cosubstrate involved in multiple crucial biochemical pathways, including the biosynthesis of neurotransmitters, which is why it can be beneficial for mood, but also for hormones. We can assess its concentrations in the blood, as well as in the cerebral spinal fluid (CSF). SAMe is something that has been in the human body since the beginning of time, but yet it was only discovered back in 1952. SAMe stands for S-adenosyl-L-methionine.†
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Mood and Brain Health Benefits
There have been numerous human clinical trials utilizing SAMe in terms of supplementation for clinical depression. The Journal of Clinical Psychiatry, back in 2009, published their findings saying that there is evidence that supports the use of this supplement for the treatment of major depressive disorder. There are so many different antidepressant prescription medications that are available, but many people don’t respond well to them. People get put on one antidepressant, maybe they feel better for a few months and the next thing they’re back to their low mood. Researchers have looked at SAMe, this endogenously-occurring substance, and said that if someone is low in SAMe and we bring that level back up to where it should be, perhaps this can help to stabilize their mood.†
Learn more about the relationship between SAMe and mood by listening to the full podcast episode.
SAMe and Methylation
Researchers noted that if SAMe was dealing with other pathways, it certainly goes beyond just neurotransmitters. We also know that it’s affecting hormones and we know that it can affect different methylation pathways. Its involvement in methylation is probably one of its most important processes because it acts as a methyl donor to support a multitude of different chemical reactions.†
We have these different, very important biochemical processes that occur and rely on methylation, including things such as the synthesis of our nucleic acids for DNA and RNA, phospholipids that help to protect our cellular membranes and mineral metabolism. We’ve even been able to recognize the role that it plays when it comes to things like Alzheimer’s disease and inflammatory conditions. There are multiple studies out there looking at this supplement for osteoarthritis patients. Some of these studies in people have compared oral SAMe supplementation with NSAIDs, including acetaminophen and ibuprofen. Researchers have found that people actually had similar pain relief utilizing SAMe compared to the NSAIDs, but didn’t have any of those side effects. This is really, really important.†
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Then we can look at the liver. We know that non-alcoholic fatty liver disease is a problem throughout the world that is primarily brought on by diet. SAMe, when we think about that methylation process in relation to detoxification pathways, plays a key role in this as well.†
Tune into the full podcast episode for more information on the various benefits of SAMe.
What do you think about this supplement? How do you help support healthy hormone levels in your body? Leave us a comment below to join the discussion!
Thank you for tuning in to the Invite Health Podcast. You can find all of our episodes for free wherever you listen to podcasts or by visiting www.invitehealth.com/podcast. Make sure you subscribe and leave us a review! Follow us on Facebook, Twitter and Instagram at Invite Health today. We’ll see you next time on another episode of the Invite Health Podcast.
Studies Show This Unique Collagen Eases Inflammation – InVite Health Podcast, Episode 286
UC-IIⓇ is really unique. It’s an undenatured type two collagen. Studies has shown that UC-IIⓇ can help ease inflammation in the body.
What To do About Bursitis, A Painful Joint Condition – InVite Health Podcast, Episode 258
Bursitis is a painful condition near your joints. It has to do with these small, squishy, fluid-filled sacs called bursa. There are lifestyle changes that can protect your bursa, including supplementation and exercise.
Targeted Approach To Burn Belly Fat – InVite Health Podcast, Episode 250
belly fat
Invite Health Podcast, Episode hosted by Amanda Williams, MPH
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With the rate at which diabetes, obesity and other metabolic disorders are on the rise in this country, it’s no wonder that people are seeking out different ways to improve upon lean muscle mass and to help enhance their body fat ratio. These are all things that are certainly important when we talk about the way that fat is distributed throughout the body and how much of an impact too much excess weight can have, especially through the abdomen.
It has been known for a very long time, in both men and women, that when you carry too much excess belly fat, it generates a significant risk when it comes to cardiovascular disease. Wouldn’t it be nice if there was something that came from nature that would be supportive to that belly fat while also providing antioxidant benefits throughout the body that can help at that cellular level. Today, I’m going to talk about CLA, which is Conjugated Linoleic Acid. The way that CLA has been researched is really quite interesting because it’s been shown to be quite effective across the spectrum for targeting many different problems that can arise through the aging process and in the setting of chronic diseases, while also placing a lot of focus on healthy weight, especially on belly fat.†
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What is CLA?
What we know about Conjugated Linoleic Acid is that it’s basically a collective term used to designate different structures of Linoleic Acid. One thing we know about Linoleic Acid by itself is it can actually be pro-inflammatory, so actually driving up inflammation in the body. When it’s in its conjugated form, it actually does a significant amount of benefit when it comes to lowering inflammation.
The benefits of CLA
One of the big drivers for CLA in terms of public knowledge of it is because of the obesity pandemic that we are dealing with, not only here in America but throughout the world. There was a lot of early research where they wondered if a lack of CLA could actually be a driving force for greater fat deposits throughout the body and less of that leaner muscle mass.
A lot of the original studies that came out with that were looking specifically at the levels of CLA. There was an interesting study that they did in Norway many years ago looking at CLA supplementation and the subjects in that study actually lost up to 20% of their body fat in three months without even changing their diet.
Tune into the full podcast episode to learn more about these early studies.
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CLA plays a really important role in thermogenesis, or natural fat burning, which is why it’s been pushed to the forefront of being beneficial for those who are trying to shave off some of that excess belly fat. Now is this something that happens over night? No, certainly not. The other thing that I like people to recognize about CLA is that it actually yields a very powerful antioxidant property to it, which is why it’s been looked at in the setting of cardiovascular disease and looking at its benefit for targeting oxidation that can be very detrimental to the heart, as well as the blood vessels. There’s a lot of research out there looking at how dietary Conjugated Linoleic Acid can reduce plasma lipoprotein levels, which refers to bad cholesterol levels. They found this when they were looking at disease states such as atherosclerosis and high cholesterol.
Learn more about the benefits and importance of CLA by tuning into the full podcast episode.