Nutrition. Vitamins. You.
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Written by Melissa Bistricer, RDN
For further questions or concerns email me at mbistricer@invitehealth.com
Did you know that the brain is mostly made up of fat and is the fattest organ in the human body? The human brain has the ability to generate ~23 watts of power when awake. If you feel a cognitive dysfunction, this can alter the brain function leading to complicated issues such as memory loss, or decreased energy. So, let’s learn about the ways we can help improve your brain function.†
Brain health is defined as the preservation of optimal brain integrity with cognitive function.1 Brain function can be affected as we age with a stable function called mild cognitive impairment and then progressing to worse stages like brain diseases such as Dementia or Alzheimer’s disease. There are changes as individual’s age and make lifestyle adjustments to positively impact the brain.†
Mild cognitive impairment is generally expected as we get older and age.2 Individuals with mild cognitive impairments still have the ability to perform normal functions. Some minor memory loss can occur and is often called “senior moments.” Even though some individuals with mild cognitive impairment remain stable, half of them progress to Dementia. Though, there are ways to prevent the progression by controlling risk factors with lifestyle modifications. Lifestyle modifications that are discussed to benefit brain health can be exercise, cognitively stimulating activities, sleep, and nutrition.† 3
The MIND diet has been studied and is recommended for individuals with cognitive decline. The MIND diet is a combination of the Mediterranean and DASH diet. The focus being on wholesome fruits, vegetables and whole grains. It focuses mainly on leafy vegetables 7 days a week, 2 or more servings of berries a week and fatty fish like salmon 1 time a week or more. In the MIND diet it is recommended to avoid trans-saturated fats, hydrogenated oils, and saturated fats.†
Krill oil is shellfish derived that supplies EPA and DHA important omega-3 fatty acids. Fatty acids have to support healthy blood vessels function and circulation as well as brain health.†
A study provides insight that omega-3 polyunsaturated fats have an effect on cognitive function in the elderly population. This has been studied specifically with krill oil, a mostly omega-3-fatty acids with phosphatidylcholine.†
Acetyl-L-Carnitine, also called Alcar, provides energy to the mitochondria of the cells. The mitochondria is known as the “powerhouse” of the cells. Alpha-lipoic acid, also called ALA, is an antioxidant naturally produced in the body to help support glutathione. Alcar + ALA are combined together at InViteⓇ Health to help counteract oxidative stress in the body. Alcar has been studied for its numerous effects specifically on the brain and muscle metabolism. Alcar protects against neurotoxicity and may be an effective treatment for certain forms of depression.4 Preclinical studies suggest that ALA has free radicals, reduces inflammation and protects the brain cells from conditions like stroke, multiple sclerosis and Alzheimer’s disease.† 5
Resveratrol Max HxⓇ has naturally sourced active trans-resveratrol in the formula and powerful antioxidants like grape seed extract and quercetin. Resveratrol comes from the skin of red grapes commonly known as the “red wine antioxidant.”†
Resveratrol is a long-term treatment with adequate dosages with improved bioavailability and can possibly exert clinically significant protective effects against cognitive decline in humans.†
RESVERATROL AND BRAIN PROTECTION – INVITE HEALTH PODCAST, EPISODE 445 >> Listen now!
Grape Seed Extract contains flavonoids and is a powerful antioxidant and anti-inflammatory. Polyphenols and flavonoids maintain cellular proteostasis which is closely involved with amyloid diseases, in particular, neurodegenerative diseases. 8 Grape Seed Extract is valuable in therapeutic agents. Amyloid disease is an abnormal protein produced in the bone marrow causing deposits in any tissue or organs.†
Krill oil Advanced supports cardiovascular and brain health with the use of EPA, DHA, Astaxanthin and Omega-3 phospholipids †
Alcar + ALA supports for energy, memory, nerve health and metabolism †
Resveratrol Max HxⓇ supports brain health, cardiovascular, pulmonary and metabolic health †
For further questions or concerns related to dietary and nutritional supplement recommendations email me at mbistricer@invitehealth.com
1. Wang Y, Pan Y, Li H. What is Brain Health and why is it important? The BMJ. https://www.bmj.com/content/371/bmj.m3683#:~:text=Definition%20of%20brain%20health,-Currently%2C%20there%20is&text=Brain%20health%20 may%20therefore%20be, that%20effect%20 normal%20brain%20function. Published October 9, 2020. Accessed March 31, 2022.
2. Gauthier, Serge, et al. “Mild cognitive impairment.” The lancet 367.9518 (2006): 1262-1270.
3. Mintzer J, Donovan KA, Kindy AZ, Lock SL, Chura LR, Barracca N. Lifestyle Choices and Brain Health. Front Med (Lausanne). 2019; 6:204. Published 2019 Oct 4. doi:10.3389/fmed.2019.00204Mintzer J, Donovan KA, Kindy AZ, Lock SL, Chura LR, Barracca N. Lifestyle Choices and Brain Health. Front Med (Lausanne). 2019; 6:204. Published 2019 Oct 4. doi:10.3389/fmed.2019.00204
4. Smeland OB, Meisingset TW, Borges K, Sonnewald U. Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice. Neurochem Int. 2012; 61(1):100-107. doi:10.1016/j.neuint.2012.04.008
5. Alpha lipoic acid. Alzheimer’s Drug Discovery Foundation. https://www.alzdiscovery.org/cognitive-vitality/ratings/alpha-lipoic-acid#:~:text=Preclinical%20research%20 suggests%20that%20 ALA, multiple%20sclerosis%2C%20and%20Alzheimer’s%20disease. Accessed April 1, 2022.
6. Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clin Interv Aging. 2013; 8:1247-1257. doi:10.2147/CIA.S50349
7. Cicero AFG, Ruscica M, Banach M. Resveratrol and cognitive decline: a clinician perspective. Arch Med Sci. 2019; 15(4):936-943. doi:10.5114/aoms.2019.85463
8. Mahdipour R, Ebrahimzadeh-Bideskan A, Hosseini M, et al. The benefits of grape seed extract in neurological disorders and brain aging [published online ahead of print, 2022 Mar 28]. Nutr Neurosci. 2022; 1-15. doi:10.1080/1028415X.2022.2051954
New scientific evidence shows just how important the carotenoids lutein and zeaxanthin are for your memory and cognitive functions.
You’ve probably heard that green tea is good for your immune system and respiratory health, but did you know it can also benefit your memory? Learn more from Jerry Hickey, Ph.
acetylcholine
InViteⓇ Health Podcast, Episode hosted by Jerry Hickey, Ph.
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If you’re beginning to forget things more commonly than usual, having trouble learning something new or losing your train of thought during a conversation, it may be related to the age-associated drop in the important neurotransmitter acetylcholine.†
Acetylcholine is produced naturally in your brain. It also works in the rest of your body, where it is involved in muscle function, heart function and more. But we’re focusing on the brain because acetylcholine is core to forming memories and learning. This nutrient has a natural decline with age and it leads to that age-related forgetfulness. We call this subjective memory loss.†
Acetylcholine is needed for more than just remembering and learning. You also use it for problem solving. For instance, if you get off the highway at the wrong exit and need to figure out how to get back on the right track, acetylcholine is needed for that. It’s also important for logical reasoning, as well as for focus and concentration.†
So how do you restore acetylcholine in the brain and body? It’s made out of choline, which is a water-soluble B vitamin. Regular choline is hard to get into the brain and it’s not in the best foods. It is in egg yolks and you do get some in fish, but a lot of the sources of choline are things such as organ meats. The choline used in most multivitamins and B-complex formulations doesn’t get into the brain very effectively. That doesn’t mean it’s not good.†
Choline is needed for nerve health, muscle health and liver health, but the form of choline that really gets into the brain is phosphatidylcholine, which is the precursor to making acetylcholine. You can get some phosphatidylcholine in legumes, but you get a lot in krill oil. Krill is a tiny crustacean related to shrimp. When we get krill for our Krill Oil Advanced formulation, we get it from a very clean, sustainable fishery in Antarctica. When you take krill oil or get phosphatidylcholine from legumes, the phosphatidylcholine readily enters your brain. The phosphatides are very important because they help maintain the structure of the brain, as well as the proper release of neurotransmitters, but it’s the choline that’s really important for your memory.†
KRILL OIL AND FISH OIL FOR BRAIN HEALTH, PART 1 – INVITE HEALTH PODCAST, EPISODE 48. Listen Now>>
90% of Americans do not get sufficient choline in the diet, which is why a krill oil supplement can be so helpful. When you take krill, you get phosphatidylcholine that readily enters the brain. You also get the fish oils that are attached to the phosphatidylcholine. Then, if you also take Alcar with ALA, the acetyl group from that supplement will attach to the phosphatidylcholine from the krill and that helps you reestablish your acetylcholine.†
In this episode, Jerry Hickey, Ph. explains the important role that the nutrient acetylcholine plays in memory. He also offers recommendations for how to rebuild levels in the body in order to support the brain.†
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