Tag: immune health

Year Round Immune Support, Invite Health Podcast, Episode 647

Year Round Immune Support, Invite Health Podcast, Episode 647

Subscribe Today! Please see below for a complete transcript of this episode. YEAR-ROUND IMMUNE SUPPORT, INVITE HEALTH PODCAST, EPISODE 647 Hosted by Amanda Williams, MD, MPH *Intro Music* InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed health care professionals 

Springtime Health Tips, Invite Health Podcast, Episode 637

Springtime Health Tips, Invite Health Podcast, Episode 637

Subscribe Today! Please see below for a complete transcript of this episode. SPRINGTIME HEALTH TIPS, INVITEⓇ HEALTH PODCAST, EPISODE 637 Hosted by Amanda Williams, MD, MPH *Intro Music*  InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed health care professionals 

Systemic Lupus Erythematosus (SLE)- Invite Blog

Systemic Lupus Erythematosus (SLE)- Invite Blog

Written by Dr. Claire Arcidiacono, ND

For further questions or concerns email me at carcidiacono@invitehealth.com

Last time we talked about RA, (Rheumatoid Arthritis), which is an autoimmune disease that includes joint pain as well as joint damage. In this same theme we have Lupus. Systemic lupus erythematosus or lupus is a well-known autoimmune disease which involves the body’s very own immune system attacking and damaging healthy cells. Lupus can mimic many different diseases and it is often called the great imitator. Due to this fact it is often misdiagnosed, and thus appropriate treatment is often delayed. † (1)

Lupus very commonly presents with a fever, malaise, fatigue, and both muscle and joint pain. It is interesting to note that while Lupus is much more likely to develop in women it can and does occur in men. The symptoms of lupus are slightly different between the two genders. Typically, women will have a low white blood cell count, increased risk of RA, Raynaud’s syndrome and even a higher rate of psychiatric symptoms. In contrast men tend to experience more seizures, kidney disease, serositis, skin disorders and neuropathy. † (2)

Skin disorders are very common in lupus. In fact, up to 70% of people diagnosed with lupus have symptoms of the disease in their skin. The Malar rash otherwise known as the butterfly rash is a well-known symptom of lupus and occurs in 30-60% of people diagnosed with Lupus. (3) See attached picture. † (4)

Anemia is very common in lupus and develops in approximately 50% of children who have been diagnosed with lupus. In addition to anemia, it is common to develop low platelet count, low white blood cell count, and different clotting type disorders. As a fascinating aside one of the autoantibodies that are present in lupus is called anti-cardiolipin antibody and it is interesting because it can present a false positive result on a syphilis test. † (5)

Lupus can also present with symptoms that are caused by damage to the internal organs. There can be inflammation in the heart caused by the lupus which can present as pericarditis, myocarditis, endocarditis, and even atherosclerosis occurs more frequently in those with lupus. (6) Similarly, inflammation in the lungs can present with signs of pleurisy, interstitial lung disease, pulmonary hypertension/hemorrhage, and pulmonary embolism. (7) In addition to affecting the heart and lungs it is well documented that lupus can cause inflammation in the kidneys.  The inflammation associated with lupus causes symptoms of lupus nephritis in the kidneys. In fact, in lupus immunofluorescence testing shows a very particular granular appearance known as Glomerulonephritis or wine loop nephritis. † (8)

Lupus can also cause neurological symptoms such as signs of neuropsychiatric syndromes. Other neurological symptoms include headaches, seizures, polyneuropathy, cognitive disorders, anxiety, and depression and even in some people psychosis. Other complications include Guillain-Barre syndrome, meningitis, demyelinating syndrome and what are called movement disorders. While lupus has numerous effects on the neurological system, in this article, I have only reviewed the most common. (9) Lupus can also affect the eyes and vision as well. Lupus has been found to affect vision and eye health in up to 1/3 of people that have been diagnosed with lupus. (10)  Due to the fact that lupus is an autoimmune disorder there are also effects on fertility.  While most people with lupus can and do have healthy children there is an increased risk of miscarriage and the death of the child in utero † (11)

ICYMI:RHEUMATOID ARTHRITIS, INVITE HEALTH BLOG>>READ NOW!

Now you may be saying Dr. Claire this is fascinating but why bring up lupus in a series on joint health. That’s because joint pain is a big part of what lupus is. Now since this is a joint health conversation and not just an arthritis series it is important to talk about lupus since as I said it does affect our joints. More than 90% of those diagnosed with lupus will have joint pain of some degree. While lupus does not usually cause the severe destruction and distortion of the joints seen in RA, there is still joint pain that can vary in its intensity from person to person. It is important to point out that pain is very individualized. Normally a doctor will use a scale from 1 to 10 for patients to rate their pain.  What one person would term a 1/10 pain another might feel is an 8/10 on the pain scale. Being more or less sensitive to pain is nothing to be ashamed of. Since we are all different, we all experience pain in a different way. Interestingly there have been studies that suggest a possible link between lupus and RA. At this time more research is needed into this possible correlation. † (12)

Lupus is a complex autoimmune disorder and thus in order to give this topic all the attention it deserves I have decided to split this topic into two parts. The next blog will cover the risk factors for developing lupus, specific tests that can help determine if you have lupus and both conventional as well as complementary approaches to controlling symptoms of lupus. †

REFERENCES

  1. “Handout on Health: Systemic Lupus Erythematosus”. Www.niams.nih.gov. February 2015. Archived from the original on 17 June 2016. Retrieved 12 June 2016.
  2. 004). “Gender differences in systemic lupus erythematosus”. Gender Medicine1(1): 12–17. Doi: 1016/S1550-8579(04)80006-8. PMID 16115579.
  3. Harris JP, Weisman MH, eds. (2007). Head and neck manifestations of systemic disease. New York: Informa Healthcare. p. 6. ISBN 9781420017564.
  4. https://www.mayoclinic.org/diseases-conditions/lupus/symptoms-causes/syc-20365789
  5. Giannouli S, Voulgarelis M, Ziakas PD, Tzioufas AG (February 2006). “Anaemia in systemic lupus erythematosus: from pathophysiology to clinical assessment”. Annals of the Rheumatic Diseases. 65(2): 144–148. doi:1136/ard.2005.041673. PMC 1798007. PMID 16079164.
  6. Hahn BH (December 2003). “Systemic lupus erythematosus and accelerated atherosclerosis”. The New England Journal of Medicine. 349 (25): 2379–2380. doi:1056/NEJMp038168. PMID 14681501.
  7. Henderson LA, Loring SH, Gill RR, Liao KP, Ishizawar R, Kim S, et al. (March 2013). “Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies”. The Journal of Rheumatology. 40 (3): 273–281.
  8. “General Pathology Images for Immunopathology”. Archived from the original on 2007-05-10. Retrieved 2007-07-24.
  9. Kasama T, Maeoka A, Oguro N (2016). “Clinical Features of Neuropsychiatric Syndromes in Systemic Lupus Erythematosus and Other Connective Tissue Diseases”. Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders. 9: CMAMD.S37477. doi:4137/CMAMD.S37477. PMC 4718090. PMID 26819561.
  10. Dammacco R (May 2018). “Systemic lupus erythematosus and ocular involvement: an overview”. Clinical and Experimental Medicine. 18 (2): 135–149. doi:1007/s10238-017-0479-9. PMID 29243035. S2CID 13757311.
  11. Smyth A, Oliveira GH, Lahr BD, Bailey KR, Norby SM, Garovic VD (November 2010). “A systematic review and meta-analysis of pregnancy outcomes in patients with systemic lupus erythematosus and lupus nephritis”. Clinical Journal of the American Society of Nephrology. 5 (11): 2060–2068. doi:2215/CJN.00240110. PMC 3001786. PMID 20688887.
  12. Joint and Muscle Pain Archived 2007-11-09 at the Wayback Machine Lupus Foundation of America

Sleep, are you getting enough? Part 1

Sleep, are you getting enough? Part 1

Written by Allie Might, FMC, INHC, ATT The subject of sleep always seems to be on everyone’s minds, and with our busy day-to-day lives, it’s no wonder this is such a hot topic. We all know that we need sleep and that it’s important, but 

New Data, Vitamin D & the Immune System. Invite Health Podcast, Episode 610

New Data, Vitamin D & the Immune System. Invite Health Podcast, Episode 610

Subscribe Today! Please see below for a complete transcript of this episode. NEW DATA, VITAMIN D & THE IMMUNE SYSTEM, INVITEⓇ HEALTH PODCAST, EPISODE 610 Hosted by Jerry Hickey, Ph. *Intro Music* InViteⓇ Health Podcast Intro:[00:00:04] Welcome to the InViteⓇ Health Podcast where our degreed 

Zinc is key to more than Immune Health, Invite Health Podcast, Episode 609

Zinc is key to more than Immune Health, Invite Health Podcast, Episode 609


Subscribe Today!

Apple PodcastsGoogle PodcastsiHeartRadioSpotify

Please see below for a complete transcript of this episode.

 ZINC IS KEY TO MORE THAN IMMUNE HEALTH, INVITEⓇ HEALTH PODCAST, EPISODE 609

Hosted by Amanda Williams, MD, MPH

*Intro Music*

InViteⓇ Health Podcast Intro:[00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed health care professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that Invite Health has to offer at, www.invitehealth.com/podcast. First time customers can use promo code Podcast at checkout for an additional 15% off your first purchase. Let’s get started.†[00:00:34]

*Intro Music*

Amanda Williams MD, MPH: [00:00:40] When it comes to our natural immune defenses, we have to always include the mineral Zinc into a routine. But we also must understand that Zinc, like many other minerals in the body, has so many functions. And that’s what I want to drive home today. I want to talk about how Zinc is actually working in the human body. Clearly, we know that Zinc is a must when it comes to our immune system and to be able to help fend off little pesky pathogens. But we also have to recognize why having insufficient exposure to Zinc from our diet or even falling into a category of having Zinc deficiency can be so detrimental to so many systems in the human body. I am Dr. Amanda Williams, scientific director at Invite Health, and let’s talk all about Zinc. We know that Zinc is critical when it comes to our overall health and wellness. We know that it’s beneficial for our cardiovascular system as well as for the health of our brain. Most of the time we think about zinc in the setting of immune health, it’s kind of like when we think about vitamin D, we think about bone health. We know Vitamin D certainly is doing much more than just supporting healthy bones, and we see the same thing when it comes to Zinc. Now, the problem is, is that many Americans actually fall into a category of having insufficient Zinc exposure, meaning that you’re getting a little but not enough, but it’s not so little that you’re actually deficient. And we do see Zinc deficiencies in a higher rate in people who are older in age. This can be because of a few different factors. We can look at different chronic disease states that have definitely been linked to lowering our Zinc status. We can also look at certain medications that have been known to lower or deplete our Zinc storage, things that elderly folks are commonly prescribed, things like ACE inhibitors to lower blood pressure. ACE inhibitors include drugs that end in PRIL, like Lisinopril, for example. We can see how the different diuretics, things like hydrochlorothiazide can lower your Zinc storage, loop diuretics such as Furosemide or Lasix can certainly do this. Proton pump inhibitors, yes, the old Nexiums of the world can certainly lower the Zinc levels. So now we can take a little pause and we can say how many older individuals are on one or more of these drugs. And you can see where that zinc depletion can start to come from, and then we tie in or correlate in the different disease states that are known to have zinc depletion.†[00:03:33]

[00:03:34] When you look at individuals who have type two diabetes, we can see a clear distinction or an association between low levels of zinc and control of diabetes. So if you have good control over your diabetes, the likelihood that you have a zinc insufficiency or deficiency not that high, but we do certainly see this strong correlation. We understand that when it comes to things like vision, health, age related macular degeneration, Zinc plays a critical role into the development of this. If you have inadequate Zinc exposure in your diet and you’re not supplementing with Zinc, then the likelihood of developing Age-Related Macular Degeneration will go up. They did a really interesting study over in Australia and they found that participants who were taking Zinc from either food or via supplementation, had a close to 50% lower risk of developing age related macular degeneration, that’s pretty impressive. So if we recognize that there are certain health conditions, there are certain medications that can create havoc when it comes to our Zinc levels, then we have to realize that Zinc is more than just for the immune system. Zinc must be pretty critical in many different biological pathways and roles. And we do see this, we can see how it is that Zinc is working at multiple different mechanisms, which is why we can tie in Zinc issues when it comes to neurological disorders, when it comes to autoimmune conditions. And this is why we always want to make sure that we are getting Zinc as part of our daily supplementation routine. It’s one of our most important minerals when it comes to the creation of a key antioxidant in the body known as superoxide dismutase, without superoxide dismutase, that means we have lost an innate ability to fight off free radicals and oxidative stress. Now, interestingly enough, they know that type two diabetics who have low serum superoxide dismutase levels have a greater likelihood of having carotid artery stenosis, meaning that vessel that runs up the side of your neck, that is more likely to be gummed up or clogged up in the setting of diabetes. What do we also know about diabetics? There’s a strong correlation between Zinc insufficiency in proper Zinc absorption in diabetics. So you can start to see, okay, if a diabetic doesn’t have enough Zinc in terms of dietary intake and they’re not supplementing with Zinc. This means the body has less Zinc available to make superoxide dismutase, which now puts that diabetic at a greater risk of a potential cardiovascular event because of the narrowing of that key vessel running into the brain, very important.† [00:06:41]

ICYMI:GETTING TO KNOW ZINC – INVITE HEALTH PODCAST, EPISODE 516>>LISTEN NOW

[00:06:42] Now we can just stay in the lane of just thinking our immune health, and clearly, the studies that are out there indicate that when we have good Zinc levels in our body, the immune system has a better opportunity to fight off and recover from different infections. As a matter of fact, when it comes to wound healing, we know that Zinc is critical to this. I oftentimes will tell people if they’re going to have to have a surgery and they are going to be doing an incision, it would be incredibly advantageous that both pre and post op people start to supplement with both vitamin C and Zinc. So this will help to promote the healing of that surgical incision in a much quicker way, this even applies to dental surgeries. So we know that when it comes to Zinc, it helps our body in terms of both the initial or the innate and the adaptive or delayed immune system. We know that it helps the body create one of its most powerful antioxidants known as superoxide dismutase. We also can recognize how it helps to protect our cellular DNA, which is really very important. So while we may always turn to Zinc to fight off the common cold, we have to realize that Zinc is doing so much more than that. You see this even in children, Zinc is key when it comes to the growth and maturation as a child is developing, when it comes to bone health, for example, which is really quite fascinating to think, oh, zinc for bone health, kind of like when we think about vitamin D for all of the different functions that Vitamin D does. But clearly we can see how when it comes to bone remodeling and the absorption of key minerals, that Zinc is very critical to playing a role in maintaining healthy bones as we age. So if we are getting older in age and our diet doesn’t have adequate Zinc and we are not supplementing with a good, high potent Zinc, then what is happening? Our immune system is more open to an infection, our bones can get weaker, our eyes are more prone to age related macular degeneration. And clearly we know that excess inflammation and oxidative stress can take over because we don’t have the ability to make superoxide dismutase. So when it comes to Zinc, know one thing that if you are not taking a comprehensive multivitamin, multi mineral formulations such as the Core multivitamin or the Performance multivitamin by InVite Health, then we definitely want to be including into our routine,the Zinc Picolinate or our Zinc Lozenge every day, because Zinc is a essential component of so many different functions in our body and we cannot overlook its key role even when it comes to thyroid function. This is often a very interesting find for many individuals who deal with Hashimoto’s and other thyroid conditions, maybe a subclinical hypothyroidism, and they will find that when they start to supplement with Zinc, they start to feel more energetic. And part of that reason is because Zinc plays as a cofactor for the manufacturing of thyroid hormone. So when it comes to mood, when it comes to blood sugar regulation, when it comes to brain function and eye health, we have to always recognize the unique property that Zinc serves us when it comes to keeping us healthy.† [00:10:31]

ICYMI:ARE DAILY MULTIVITAMIN’S IMPORTANT? – INVITE HEALTH PODCAST, EPISODE 561>>LISTEN NOW!

[00:10:33] And this is why I wanted to focus in on Zinc today, because Zinc is one of those long lost minerals that many times we just kind of put away until it’s cold and flu season. And then we take it out and say, Oh, I should be taking this. But actually Zinc is something that should be part of our everyday supplementation routine. So hopefully now, you know, a little bit more about Zinc, and remember, you can always reach out to one of our nutritionists if you have questions as to how you should be taking your zinc and what time of day, as well as if you should take it with food, without food. All of these questions can be answered from one of our health experts at Invite Health. And I want to thank you so much for tuning in to the InViteⓇ Health Podcast Remember, you can find all of our episodes for free wherever you listen to podcasts or by visiting Invitehealth.com/podcast. Do make sure that you subscribe and you leave us a review. You can follow us on Facebook, Twitter and Instagram at Invite Health. And we will see you next time for another episode of the InViteⓇ Health Podcast [00:10:33]

*Exit Music*