Subscribe Today! Please see below for a complete transcript of this episode. THE UNDERSTIMATED BENEFITS OF CRANBERRY, INVITE HEALTH PODCAST, EPISODE 652 Hosted by Jerry Hickey, PH *Intro Music* InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed health …
Tag: urinary tract infection
Subscribe Today! Please see below for a complete transcript of this episode. Go-To Supplements to Support Bladder Function, Invite Health Podcast, Episode 640 Hosted by Amanda Williams, MD, MPH *Intro Music* InViteⓇ Health Podcast Intro: [00:00:04] Welcome to the InViteⓇ Health Podcast, where our degreed …
Please see below for a complete transcript of this episode.
Bladder Pain and Pressure – InViteⓇ Health Podcast, Episode 527
Hosted by Amanda Williams, MPH
InViteⓇ Health Podcast Intro: Welcome to the InViteⓇ Health Podcast, where our degreed healthcare professionals are excited to offer you the most important health and wellness information you need to make informed choices about your health. You can learn more about the products discussed in each of these episodes and all that InViteⓇ Health has to offer at www.invitehealth.com/podcast. First time customers can use promo code PODCAST at checkout for an additional 15% off your first purchase. Let’s get started!
Amanda Williams, MPH:
[00:00:40] Have you ever heard of interstitial cystitis? This is a common issue that affects mainly women, but can also impact the urinary tract of men as well. And today I want to talk about the details of interstitial cystitis, the symptoms, what you can be doing and just how common this is. So I’m Amanda Williams, MD, MPH, Scientific Director here at InViteⓇ Health. And when it comes to our urinary system, we want to make sure that we are doing the right things when it comes to our fluid intake, when it comes to the right vitamins and minerals, as well as the foods that you eat every day that can really help to optimize and support the health of your bladder.† [00:01:26]
[00:01:27] So we know that the high antioxidant foods are certainly beneficial. Many times people have heard of cranberry, for example, when it comes to bladder health. And we know this to be the case because what the mannose, which is a carbohydrate contained in the cranberry actually does, is it creates a slippery environment within the bladder wall, which makes it very difficult for bacteria to adhere. So when in the setting of UTIs or urinary tract infections, which we know are incredibly common, it’s one of the most common causes for outpatient infections in this country, and the lifetime incidence is somewhere around 50, 60% for women who will experience a UTI throughout the course of their lives. And then you have women who will have recurrent UTIs. Now, as men get older, the prevalence or occurrence rate of urinary tract infections begins to go up because of incomplete bladder emptying, so men are more prone to urinary tract infections as they age.† [00:02:34]
[00:02:35] So we know that this is a common problem, but we also know that there is something known as interstitial cystitis that can really be problematic. And what interstitial cystitis is, sometimes they also call it bladder pain syndrome, but this is a chronic condition, and it’s a feeling of pain or pressure in the bladder area. Some people will describe it even as a burning sensation, but it’s not associated directly with a UTI. So it’s bladder pressure, bladder pain, sometimes it’s just described in general as like pelvic pain. The pain can range from mild and irritating to significant and very severe.† [00:03:20]
[00:03:21] We know that when it comes to interstitial cystitis, oftentimes doctors are at a loss as to what to necessarily do because it’s not like, “OK, well, they have a urinary tract infection. Let’s give them an antibiotic,” because this is not going to create any type of relief for those who are dealing with cystitis. And so cystitis, bladder pain syndrome, kind of the two go hand-in-hand. It’s interchangeable just depending upon how your doctor may describe it to you. But we know that this is a common condition. Initially, they thought that cystitis affected roughly around 2 out of every 100,000, in particular, women. Now they recognize that this is probably more like 10 to 15% of women who experience this problem. And I’ve talked to many women throughout the years, and they’re generally at a loss as to how to manage this because there is no good direct targeted treatment.† [00:04:27]
[00:04:28] So when you look at the pathophysiology of this, it’s even fairly well unknown, one could say, because they don’t necessarily know why it is that women are prone to experiencing this bladder pressure, bladder pain. You know, you can look at pelvic floor dysfunction. We can look at certainly a dysregulated immune system, increase in inflammation in the body. So chronic inflammation can certainly drive this. So you can look at women, perhaps, who have a history of diabetes or high blood pressure may be more prone to developing cystitis. So there are many unknowns when it comes to cystitis, but we definitely know that the prevalence is relatively high. Now, keep in mind, there are many women who suffer with this and even men as well, so this is not just, you know, solely women who experience this, who can have this problem and are never necessarily diagnosed. Maybe they never mentioned it to their doctor, or maybe they don’t see their doctor on a regular basis. But we definitely know that this is a problem not only here in the United States but worldwide. And we can tie those chronic disease states, things like diabetes and kidney disease and, you know, heart disease into putting someone into a greater risk for developing interstitial cystitis.† [00:05:54]
[00:05:55] But what can we do once someone has this? Because at the end of the day, if someone is dealing with interstitial cystitis, they are incredibly uncomfortable and having just this irritated bladder wall all of the time. And this can actually get to the level where it creates scarring within the bladder, which can then really be incredibly problematic. So when it comes to traditional approach, most even urologists are once again at a loss as to how to manage these patients. And so when you look at the, you know, diagnosis and the treatment, they generally once again are looking at, “OK, let’s try antibiotics. Maybe there’s an underlying infection and we’re just missing this and this is what’s creating this inflammation in this pain within the bladder.” But for many people who have cystitis, the antibiotic is not going to do anything because this is not where the problem resides. The problem resides within that oxidative stress and the inflammation. So what we do know is that there are many different nutrients that someone who is dealing with interstitial cystitis can utilize that can provide a lot of support.† [00:07:21]
[00:07:22] We can look at an amino acid known as arginine. L-arginine, we know is very beneficial when it comes to many functions in the body, including blood pressure regulation through its action of releasing nitric oxide. But they did an interesting study where they took a group of people who had diagnosed interstitial cystitis and they gave them 1500mg of arginine daily. And then they assessed if they had any improvement on their pain intensity and the pain frequency, as well as any other urinary symptoms that they may have been experiencing. Maybe that, you know, urge to have to go to the bathroom more often. And what they found was that the group that was given arginine compared to the placebo group did really well in terms of overall improvement across all areas. Now they did another study where they compared L-arginine to a drug called elmiron, and elmiron oftentimes is another one of those go to trial by errors that a doctor may prescribe to someone who is dealing with interstitial cystitis. That’s actually a prescription medication whose indication is to treat bladder pain and discomfort. What we know is that elmiron comes with significant side effects, and there’s actually lawsuits out there against that drug because people who have been prescribed that have actually experienced detrimental effects on their vision and even had, to serious degrees, loss of sight from being on this medication. So OK, well, if the arginine, this amino acid, is working better than the prescription medication, then perhaps that’s what they should be utilizing, right? Well, we know that the arginine can be very helpful and it’s working on a couple of different fronts. Number one, we’re getting better blood flow, oxygenation, targeting oxidative stress, targeting the inflammation within the bladder.† [00:09:32]
[00:09:33] And then we partner this up with omega-3 fatty acids, fish oil in particular. They have looked at dietary intake of those who suffer from cystitis and those who have high amounts of omega-3s in their diet will have a lessening of those symptoms. So as soon as they start to incorporate in things like salmon and walnuts, avocados into their routine, their inflammatory levels in the body begin to go down and they start to get improvement overall within the bladder. So we know that supplementation with fish oil is also incredibly beneficial for anyone who is dealing with that type of bladder irritation or bladder pain that is not associated with a urinary tract infection.† [00:10:18]
[00:10:19] Now here’s another little fun tip is quercetin. That powerful bioflavonoid has been shown in clinical trials to be very, very powerful when it comes to patients who have interstitial cystitis. So all of those symptoms that are driven up because of the inflammation. We know that when you have foods that are high in quercetin, things like broccoli and onions and blueberry, that this is going to lower the inflammation in the body. But when we take quercetin as a supplement, they have been able to show how it could actually reduce pelvic pain. And this was shown in men who have prostatitis, so inflammation within their prostate, but also in patients who have interstitial cystitis.† [00:11:06]
[00:11:07] Now, I oftentimes will even partner the quercetin up with bromelain. Remember, bromelain is coming from the stem of the pineapple. I have found that many folks who deal with cystitis and are in this chronic state of discomfort that when they include in quercetin along with bromelain, bromelain, taking that on an empty stomach around 1000mg twice a day, quercetin at least 1000mg per day, and then the fish oil at least 2000mg of your omega-3s per day, and then we look at the arginine, at minimum, we want to be using 1000mg per day, upwards to 2000mg per day. This can really yield an awful lot of support for someone who is dealing with that chronic bladder pain, pressure and discomfort.† [00:11:58]
[00:11:59] And you think about other things that we need to create balance in. So if someone has low Vitamin D, low magnesium, these can also be driving reasons that are exacerbating that pain and inflammation within the bladder. So it’s a comprehensive approach, but it’s definitely much more manageable than traditional doctors lead on to, to believe because they never look at the foods, they never look at supplementation. And we definitely can see through scientific research that when it comes to getting interstitial cystitis under control, that there are many different nutrients and lifestyle modifications that can certainly lead you to a point where this very debilitating at times problem can be managed, controlled and not be that pain in your bladder.† [00:12:56]
[00:12:57] So that’s all that I have for you for today. I want to thank you so much for tuning in to the InViteⓇ Health Podcast. Remember, you can find all of our episodes for free wherever you listen to podcasts or by visiting invitehealth.com/podcast. Now, do make sure that you subscribe and you leave us a review. You can follow us on Facebook, Twitter and Instagram, and we will see you next time for another episode of the InViteⓇ Health Podcast.† [00:12:57]
Don’t wait until something is wrong to pay attention to your blood sugar levels and kidney health. Learn about the nutrients you need to help keep them both in balance.
You may have noticed that your urine can change color based on the foods you eat, but did you know this can also be caused by medications or health conditions? Learn more about this from Jerry Hickey, Ph.
Studies Show D-Mannose Helps Protect Against Urinary Tract Infections – Invite Health Podcast, Episode 169
Invite Health Podcast, Episode hosted by Jerry Hickey. Ph
Women are more prone to urinary tract infections than men. Eventually, 1 in 5 women will develop a Urinary Tract Infection. They’re very common.
WHAT IS A URINARY TRACT INFECTION?
A urinary tract infection (UTI) is an infection in any part of the urinary system. It could be your kidneys, ureters, bladder and urethra. However, most of the infections in the urinary tract involve the lower urinary tract — just the bladder and the urethra. The most common cause of a UTI is a bacterium that normally lives in your intestinal tract called E. coli (Escherichia coli). Other bacteria can also cause a UTI, but E. coli is the most common. If you don’t treat the infection, it usually doesn’t get better, and if it reaches the kidneys, it can cause a problem.
Women are more prone to UTIs because their urethra is shorter than a man’s, so it takes less time for bacteria to reach their bladder. This makes it is easier for bacteria to reach the bladder and cause an infection. Some women suffer frequently with UTIs.
HOW TO REDUCE THE RISK OF UTIS, ACCORDING TO MEDICAL PROFESSIONALS:
- Drink plenty of liquids, especially water.Drinking water helps dilute your urine, ensuring that you’ll urinate more frequently and thus flush out bacteria with a stronger stream of urine.
- Drink cranberry juice. Cranberries are loaded with polyphenols. They make the urinary tract more slippery, so it’s hard for the bacterium to attach to your urinary tract. This makes it easier to flush the bacteria out of your body when you urinate.
- Wipe from front to back. Doing so after urinating and after a bowel movement helps prevent bacteria in the anal region from spreading to the vagina and urethra. It’s an important thing because that’s how the E. coli commonly infects women.
- After intercourse, empty your bladder as soon as possible. Drink a full glass of water to help flush out the bacteria, because you can get a urinary tract infection during intercourse.
- Avoid potentially irritating feminine products. Some feminine products are very irritating, like deodorant sprays and douches and powders, which can irritate the urethra and cause inflammation in the area.
In addition to the tips above, here’s what I recommend to women who contact me for advice:
- Cranberry capsules may work better than cranberry juice, since most juices contain a lot of added sugar. Capsules still deliver polyphenols to your body without the sugar.†
- Hibiscus Tea tastes delicious and has been known to cleanse the urinary tract. You can mix cranberry or white or green tea with it.†
- Probiotic Bacteria containing certain strains of Lactobacilli start to reach the urinary tract within a week of starting a supplement, helping to prevent future UTIs, as well as vaginal yeast infections.†
- D-Mannose is a sugar we naturally make in our body. To infect you, bacteria have to stick onto the wall of your urethra. Taking a supplement of D-Mannose makes the urinary tract wall slippery and prevents certain bacteria from sticking to the walls of the urinary tract. When you urinate, the pressure of the urine flushes out the bacteria helping to prevent an infection. Research shows that taking d-mannose might reduce symptoms of UTIs, such as burning and increased urination. Also, taking D-mannose powder after a UTI often prevents them from reoccurring.†
Clinical Studies on D-Mannose for UTIs
The American Journal of Obstetrics and Gynecology shared a study from August 2020, done by The University of Pittsburgh Department of Obstetrics and Gynecology and Reproductive Sciences and Washington University School of Medicine Department of Obstetrics and Gynecology and Division of Female Pelvic Medicine. They performed a systemic review, sorting through all available data on d-mannose to determine if it had any effect on preventing future urinary tract infections. Through their research, they found that the risk of future UTIs decreased by 77% when on d-mannose, whereas antibiotics only decreased the risk by 61%. They said, “D-mannose appears protective for recurrent urinary tract infections versus placebo with possibly similar effectiveness as antibiotics.” In other words, the d-mannose works and that’s preventing a future urinary tract infection.
The journal Climacteric shared a study from April 23, 2020, done by the University of Pisa’s Department of Obstetrics and Gynecology and the University of Madinah and Jos (10:04) They worked with 40 post-menopausal women who were undergoing prolapse surgery for bulging urinary bladders. The women were split into two groups: one which took a d-mannose with cranberry supplement twice a day for two weeks and another which took a placebo at the same frequency. This was to test to see if the d-mannose would prevent complications like UTIs and cystitis. What they found was the women on the d-mannose and the cranberry did significantly better. They had fewer complications from the surgery. The lower urinary tract symptoms connected with this surgery after menopause was really helped by combining d-mannose and cranberry.
The World Journal of Urology shared a study of 308 women who had severe UTIs, which were also recurring. The women were split into three groups. One group went on d-mannose for six months, another on a placebo, and a third on a powerful antibiotic called nitrofurantoin, which is commonly used to prevent and treat UTIs. The women on the d-mannose and nitrofurantoin, in comparison to the women who received placebo, experienced far fewer UTI episodes over the six month period. The women on d-mannose had fewer infections than the women on the antibiotic. It was actually more protective than the antibiotic.
The journal Minerva Gynecologia shared a study done at The University of Siena. They looked at how, as women age, it affects their urinary tract and it makes them more susceptible to urinary tract infections. With reduced estrogen after menopause, cystitis becomes pretty common. They also develop bladder inflammation. So what they did was they gave them d-mannose, 150 women age 40-50 suffering with recurring cystitis with or without bacteria. They found that 92% of the women on d-mannose saw improvement in their urinary tract symptoms and UTIs.
The University of Sapienza in Rome’s Department of Gynecology-Obstetrics and Urology, did a study on women with current UTIs, which was shared in the European Review for Medical and Pharmacological Sciences. They found that d-mannose helps you get over a UTI and that it strongly prevented future infections. With d-mannose, only 4.5% of women developed future UTIs. Without d-mannose, a third of them developed future UTIs.
Thank you for tuning in to the Invite Health Podcast. You can find all of our episodes for free wherever you listen to podcasts or by visiting www.invitehealth.com/podcast. Make sure you subscribe and leave us a review! Follow us on Facebook, Twitter and Instagram at Invite Health today. We’ll see you next time on another episode of the Invite Health Podcast.